Mouse Gene Fbxo16 (ENSMUST00000224629.1) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus F-box protein 16 (Fbxo16), transcript variant 1, mRNA. (from RefSeq NM_015795)
Gencode Transcript: ENSMUST00000224629.1
Gencode Gene: ENSMUSG00000034532.9
Transcript (Including UTRs)
   Position: mm10 chr14:65,266,618-65,323,971 Size: 57,354 Total Exon Count: 8 Strand: +
Coding Region
   Position: mm10 chr14:65,270,737-65,321,398 Size: 50,662 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:65,266,618-65,323,971)mRNA (may differ from genome)Protein (334 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: FBX16_MOUSE
DESCRIPTION: RecName: Full=F-box only protein 16;
FUNCTION: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
SUBUNIT: Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity).
SIMILARITY: Contains 1 F-box domain.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -53.40203-0.263 Picture PostScript Text
3' UTR -784.602573-0.305 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001810 - F-box_dom_cyclin-like

Pfam Domains:
PF00646 - F-box domain
PF12937 - F-box-like

SCOP Domains:
81383 - F-box domain

ModBase Predicted Comparative 3D Structure on Q9QZM9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGDEnsembl   
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003674 molecular_function

Biological Process:
GO:0008150 biological_process

Cellular Component:
GO:0005575 cellular_component


-  Descriptions from all associated GenBank mRNAs
  AK164657 - Mus musculus 13 days embryo stomach cDNA, RIKEN full-length enriched library, clone:D530022B05 product:F-box only protein 16, full insert sequence.
AK081947 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130089A04 product:f-box only protein 16, full insert sequence.
AF176531 - Mus musculus F-box protein FBX16 mRNA, complete cds.
AK077043 - Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4932435C24 product:f-box only protein 16, full insert sequence.
AK043554 - Mus musculus 10 days neonate cortex cDNA, RIKEN full-length enriched library, clone:A830007L16 product:similar to F-BOX PROTEIN FBX16 [Mus musculus], full insert sequence.
BC086690 - Mus musculus F-box protein 16, mRNA (cDNA clone MGC:113782 IMAGE:30683387), complete cds.
BC115890 - Mus musculus F-box protein 16, mRNA (cDNA clone MGC:144594 IMAGE:40103787), complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: Fbx16, FBX16_MOUSE, NM_015795, Q3TP74, Q8C5V6, Q9QZM9, uc007ujd.1, uc007ujd.2
UCSC ID: uc007ujd.2
RefSeq Accession: NM_015795
Protein: Q9QZM9 (aka FBX16_MOUSE or FX16_MOUSE)
CCDS: CCDS36956.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.