Mouse Gene Mbnl2 (uc007uzw.1) Description and Page Index
  Description: muscleblind-like protein 2 isoform 2
Transcript (Including UTRs)
   Position: mm9 chr14:120,724,016-120,830,920 Size: 106,905 Total Exon Count: 6 Strand: +
Coding Region
   Position: mm9 chr14:120,724,461-120,828,284 Size: 103,824 Coding Exon Count: 6 

Page IndexSequence and LinksCTDMicroarray ExpressionRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2011-03-02

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:120,724,016-120,830,920)mRNA (may differ from genome)Protein (361 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAllen Brain Atlas
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
PubMedStanford SOURCEUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from GNF1M Mouse Chip

    
     
      
       
     
    
   
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Absolute
     
     
     
    
   
     
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Absolute

GNF Expression Atlas Data from U74b Mouse Chip

          
Ratios
          
Absolute

Affymetrix All Exon Microarrays

           
Ratios

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -125.46445-0.282 Picture PostScript Text
3' UTR -609.092636-0.231 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000571 - Znf_CCCH

Pfam Domains:
PF00642 - Zinc finger C-x8-C-x5-C-x3-H type (and similar)

ModBase Predicted Comparative 3D Structure on D0EX61
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologGenome BrowserNo ortholog
Gene Details   Gene Details 
Gene Sorter   Gene Sorter 
  Ensembl WormBase 
  Protein Sequence Protein Sequence 
  Alignment Alignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0046872 metal ion binding


-  Descriptions from all associated GenBank mRNAs
  AK220470 - Mus musculus mRNA for mKIAA4072 protein.
AK151913 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830042L08 product:muscleblind-like 2, full insert sequence.
AK151926 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830043F20 product:muscleblind-like 2, full insert sequence.
AK151957 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830043N18 product:muscleblind-like 2, full insert sequence.
AK164372 - Mus musculus 12 days embryo spinal ganglion cDNA, RIKEN full-length enriched library, clone:D130076O03 product:muscleblind-like 2, full insert sequence.
AK028797 - Mus musculus 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732457D15 product:ZINC FINGER PROTEIN homolog [Homo sapiens], full insert sequence.
AK085709 - Mus musculus 10 days lactation, adult female mammary gland cDNA, RIKEN full-length enriched library, clone:D730020H24 product:ZINC FINGER PROTEIN homolog [Homo sapiens], full insert sequence.
AK159213 - Mus musculus osteoclast-like cell cDNA, RIKEN full-length enriched library, clone:I420010C06 product:muscleblind-like 2, full insert sequence.
BC079898 - Mus musculus muscleblind-like 2, mRNA (cDNA clone IMAGE:30621554).
BC023895 - Mus musculus muscleblind-like 2, mRNA (cDNA clone IMAGE:5321034), with apparent retained intron.
AK148740 - Mus musculus 2 days neonate sympathetic ganglion cDNA, RIKEN full-length enriched library, clone:7120441J03 product:unclassifiable, full insert sequence.
AK178232 - Mus musculus cDNA, clone:Y0G0105O16, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022738, based on BLAT search.
AK210843 - Mus musculus cDNA, clone:Y2G0119M22, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022738, based on BLAT search.
AK178090 - Mus musculus cDNA, clone:Y0G0105G09, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022738, based on BLAT search.
AK167479 - Mus musculus 11 days pregnant adult female placenta cDNA, RIKEN full-length enriched library, clone:I530016L06 product:muscleblind-like 2, full insert sequence.
AK153261 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830130A11 product:muscleblind-like 2, full insert sequence.
AK167694 - Mus musculus 11 days pregnant adult female placenta cDNA, RIKEN full-length enriched library, clone:I530028M09 product:muscleblind-like 2, full insert sequence.
BC075665 - Mus musculus muscleblind-like 2, mRNA (cDNA clone MGC:99980 IMAGE:30605146), complete cds.
BC020406 - Mus musculus muscleblind-like 2, mRNA (cDNA clone IMAGE:3663266).
AK195501 - Mus musculus cDNA, clone:Y1G0118L02, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000040689, based on BLAT search.
BC026711 - Mus musculus muscleblind-like 2, mRNA (cDNA clone IMAGE:5358037).
GQ906534 - Mus musculus muscleblind-like 2 isoform 3 (Mbnl2) mRNA, complete cds, alternatively spliced.
AK206292 - Mus musculus cDNA, clone:Y2G0104F23, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022738, based on BLAT search.
AK216404 - Mus musculus cDNA, clone:Y2G0138E05, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022738, based on BLAT search.
AK177332 - Mus musculus cDNA, clone:Y0G0102G13, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022738, based on BLAT search.
AK192385 - Mus musculus cDNA, clone:Y1G0108L18, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022738, based on BLAT search.
AK217689 - Mus musculus cDNA, clone:Y2G0142K02, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000022738, based on BLAT search.
AK003316 - Mus musculus 18-day embryo whole body cDNA, RIKEN full-length enriched library, clone:1110002M11 product:unclassifiable, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: AK167694, D0EX61, D0EX61_MOUSE, NM_207515, NP_997398
UCSC ID: uc007uzw.1
RefSeq Accession: NM_207515
Protein: D0EX61

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AK167694.1
exon count: 6CDS single in 3' UTR: no RNA size: 2465
ORF size: 1086CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2175.00frame shift in genome: no % Coverage: 96.43
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.