Mouse Gene Ccn3 (ENSMUST00000050027.8) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus cellular communication network factor 3 (Ccn3), mRNA. (from RefSeq NM_010930)
Gencode Transcript: ENSMUST00000050027.8
Gencode Gene: ENSMUSG00000037362.8
Transcript (Including UTRs)
Position: mm10 chr15:54,745,702-54,754,039 Size: 8,338 Total Exon Count: 5 Strand: +
Coding Region
Position: mm10 chr15:54,745,972-54,752,505 Size: 6,534 Coding Exon Count: 5
Data last updated at UCSC: 2019-09-19
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: NOV_MOUSE
DESCRIPTION: RecName: Full=Protein NOV homolog; Short=NovH; AltName: Full=CCN family member 3; AltName: Full=Nephroblastoma-overexpressed gene protein homolog; Flags: Precursor;
FUNCTION: Immediate-early protein likely to play a role in cell growth regulation (By similarity).SUBUNIT: Interacts with FBLN1 (By similarity).SUBCELLULAR LOCATION: Secreted.SIMILARITY: Belongs to the CCN family.SIMILARITY: Contains 1 CTCK (C-terminal cystine knot-like) domain.SIMILARITY: Contains 1 IGFBP N-terminal domain.SIMILARITY: Contains 1 TSP type-1 domain.SIMILARITY: Contains 1 VWFC domain.
Primer design for this transcript
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR006208 - Cys_knot
IPR006207 - Cys_knot_C
IPR000867 - IGFBP-like
IPR012395 - IGFBP_CNN
IPR017891 - Insulin_GF-bd_Cys-rich_CS
IPR000884 - Thrombospondin_1_rpt
IPR001007 - VWF_C
Pfam Domains: PF00007 - Cystine-knot domain
PF00093 - von Willebrand factor type C domain
PF00219 - Insulin-like growth factor binding protein
SCOP Domains: 57603 - FnI-like domain
57184 - Growth factor receptor domain
82895 - TSP-1 type 1 repeat
ModBase Predicted Comparative 3D Structure on Q64299
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK081944 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130088N23 product:nephroblastoma overexpressed gene, full insert sequence.AK081310 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130003E23 product:nephroblastoma overexpressed gene, full insert sequence.AK136407 - Mus musculus adult male colon cDNA, RIKEN full-length enriched library, clone:9030006D15 product:NOV protein homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog), full insert sequence.AK155048 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630118I18 product:NOV protein homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog), full insert sequence.BC003774 - Mus musculus nephroblastoma overexpressed gene, mRNA (cDNA clone MGC:5979 IMAGE:3494896), complete cds.X96585 - M.musculus mRNA for NOV protein.AK039481 - Mus musculus adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330049G02 product:nephroblastoma overexpressed gene, full insert sequence.Y09257 - M.musculus mRNA for NOV protein.
Other Names for This Gene
Alternate Gene Symbols: NM_010930, Nov, NOV_MOUSE, Q64299, Q8CA67, uc007vrn.1, uc007vrn.2, uc007vrn.3UCSC ID: uc007vrn.3RefSeq Accession: NM_010930
Protein: Q64299
(aka NOV_MOUSE)
CCDS: CCDS27471.1
Gene Model Information
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.