Mouse Gene Pdgfb (ENSMUST00000000500.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus platelet derived growth factor, B polypeptide (Pdgfb), mRNA. (from RefSeq NM_011057)
Gencode Transcript: ENSMUST00000000500.7
Gencode Gene: ENSMUSG00000000489.7
Transcript (Including UTRs)
   Position: mm10 chr15:79,995,874-80,014,808 Size: 18,935 Total Exon Count: 7 Strand: -
Coding Region
   Position: mm10 chr15:79,997,580-80,013,998 Size: 16,419 Coding Exon Count: 6 

Page IndexSequence and LinksPrimersCTDRNA StructureOther Species
mRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr15:79,995,874-80,014,808)mRNA (may differ from genome)Protein (241 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsPubMed
SOURCEUniProtKBWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -400.60810-0.495 Picture PostScript Text
3' UTR -511.901408-0.364 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  BC036976 - Mus musculus platelet derived growth factor, B polypeptide, mRNA (cDNA clone IMAGE:4946092), partial cds.
BC023427 - Mus musculus platelet derived growth factor, B polypeptide, mRNA (cDNA clone IMAGE:5010396), partial cds.
BC064056 - Mus musculus platelet derived growth factor, B polypeptide, mRNA (cDNA clone MGC:73598 IMAGE:1380782), complete cds.
BC053430 - Mus musculus platelet derived growth factor, B polypeptide, mRNA (cDNA clone MGC:59331 IMAGE:6330609), complete cds.
AF162784 - Mus musculus platelet-derived growth factor beta chain (Pdgfb) mRNA, complete cds.
AK087840 - Mus musculus 2 days pregnant adult female ovary cDNA, RIKEN full-length enriched library, clone:E330027M19 product:platelet derived growth factor, B polypeptide, full insert sequence.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
mmu04010 - MAPK signaling pathway
mmu04060 - Cytokine-cytokine receptor interaction
mmu04510 - Focal adhesion
mmu04540 - Gap junction
mmu04810 - Regulation of actin cytoskeleton
mmu05200 - Pathways in cancer
mmu05211 - Renal cell carcinoma
mmu05214 - Glioma
mmu05215 - Prostate cancer
mmu05218 - Melanoma

BioCarta from NCI Cancer Genome Anatomy Project
m_dbpbPathway - Transcriptional activation of dbpb from mRNA

-  Other Names for This Gene
  Alternate Gene Symbols: A0A0R4IZW4, NM_011057, uc007wuz.1, uc007wuz.2
UCSC ID: uc007wuz.2
RefSeq Accession: NM_011057
CCDS: CCDS27656.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.