Mouse Gene Ildr1 (ENSMUST00000119464.1) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus immunoglobulin-like domain containing receptor 1 (Ildr1), transcript variant 2, mRNA. (from RefSeq NM_134109)
Gencode Transcript: ENSMUST00000119464.1
Gencode Gene: ENSMUSG00000022900.14
Transcript (Including UTRs)
   Position: mm10 chr16:36,694,038-36,726,741 Size: 32,704 Total Exon Count: 8 Strand: +
Coding Region
   Position: mm10 chr16:36,694,160-36,725,536 Size: 31,377 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:36,694,038-36,726,741)mRNA (may differ from genome)Protein (516 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: ILDR1_MOUSE
DESCRIPTION: RecName: Full=Immunoglobulin-like domain-containing receptor 1; Flags: Precursor;
FUNCTION: Putative membrane receptor (By similarity).
SUBUNIT: Homooligomer (By similarity).
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (By similarity).
TISSUE SPECIFICITY: Expressed in the vestibule and in hair cells and supporting cells of the cochlea.
DEVELOPMENTAL STAGE: Expressed early in development.
SIMILARITY: Belongs to the immunoglobulin superfamily. LISCH7 family.
SIMILARITY: Contains 1 Ig-like V-type (immunoglobulin-like) domain.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -50.60122-0.415 Picture PostScript Text
3' UTR -311.401205-0.258 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007110 - Ig-like
IPR013783 - Ig-like_fold
IPR003599 - Ig_sub
IPR008664 - LISCH7

Pfam Domains:
PF05624 - Lipolysis stimulated receptor (LSR)

SCOP Domains:
48726 - Immunoglobulin

ModBase Predicted Comparative 3D Structure on Q8CBR1
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0042802 identical protein binding
GO:0070506 high-density lipoprotein particle receptor activity

Biological Process:
GO:0006898 receptor-mediated endocytosis
GO:0051260 protein homooligomerization
GO:0090277 positive regulation of peptide hormone secretion
GO:1990830 cellular response to leukemia inhibitory factor

Cellular Component:
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032991 macromolecular complex
GO:0061689 tricellular tight junction


-  Descriptions from all associated GenBank mRNAs
  AK136284 - Mus musculus adult male eyeball cDNA, RIKEN full-length enriched library, clone:7530422P03 product:hypothetical LISCH7/Immunoglobulin subtype/Cysteine-rich region profile/Ig-like domain profile containing protein, full insert sequence.
BC057644 - Mus musculus immunoglobulin-like domain containing receptor 1, mRNA (cDNA clone MGC:67902 IMAGE:4912789), complete cds.
AK050806 - Mus musculus 9 days embryo whole body cDNA, RIKEN full-length enriched library, clone:D030020N12 product:hypothetical Immunoglobulin subtype/Cysteine-rich region profile/Ig-like domain profile/Immunoglobulin-like containing protein, full insert sequence.
BC010485 - Mus musculus immunoglobulin-like domain containing receptor 1, mRNA (cDNA clone MGC:7224 IMAGE:3483341), complete cds.
AK035504 - Mus musculus adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530057G23 product:hypothetical protein, full insert sequence.
AK036844 - Mus musculus adult female vagina cDNA, RIKEN full-length enriched library, clone:9930017K14 product:UNKNOWN (PROTEIN FOR MGC:7224), full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: ILDR1_MOUSE, NM_134109, Q6PFB3, Q8CB39, Q8CBR1, Q91VS0, uc007zcs.1, uc007zcs.2, uc007zcs.3
UCSC ID: uc007zcs.3
RefSeq Accession: NM_134109
Protein: Q8CBR1 (aka ILDR1_MOUSE)
CCDS: CCDS49841.1, CCDS70718.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.