Mouse Gene Mapk8ip3 (ENSMUST00000121723.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 5, mRNA. (from RefSeq NM_001163450)
Gencode Transcript: ENSMUST00000121723.7
Gencode Gene: ENSMUSG00000024163.17
Transcript (Including UTRs)
   Position: mm10 chr17:24,897,534-24,936,929 Size: 39,396 Total Exon Count: 32 Strand: -
Coding Region
   Position: mm10 chr17:24,898,948-24,936,854 Size: 37,907 Coding Exon Count: 32 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:24,897,534-24,936,929)mRNA (may differ from genome)Protein (1306 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: E9Q6E0_MOUSE
DESCRIPTION: SubName: Full=C-Jun-amino-terminal kinase-interacting protein 3;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -40.0075-0.533 Picture PostScript Text
3' UTR -581.001414-0.411 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR019143 - JNK/Rab-associated_protein-1_N
IPR011047 - Quinonprotein_ADH-like
IPR015943 - WD40/YVTN_repeat-like_dom

Pfam Domains:
PF09744 - JNK_SAPK-associated protein-1
PF16471 - JNK-interacting protein leucine zipper II

SCOP Domains:
103657 - BAR/IMD domain-like
50952 - Soluble quinoprotein glucose dehydrogenase
50960 - TolB, C-terminal domain
63825 - YWTD domain
63829 - Calcium-dependent phosphotriesterase
69304 - Tricorn protease N-terminal domain
101898 - NHL repeat
75011 - 3-carboxy-cis,cis-mucoante lactonizing enzyme
101908 - Putative isomerase YbhE
117289 - Nucleoporin domain
50969 - YVTN repeat-like/Quinoprotein amine dehydrogenase
50974 - Nitrous oxide reductase, N-terminal domain
50978 - WD40 repeat-like
50993 - Peptidase/esterase 'gauge' domain
69322 - Tricorn protease domain 2
50998 - Quinoprotein alcohol dehydrogenase-like
51004 - C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase
82171 - DPP6 N-terminal domain-like
52540 - P-loop containing nucleoside triphosphate hydrolases
58042 - Outer membrane lipoprotein
161256 - RILP dimerisation region

ModBase Predicted Comparative 3D Structure on E9Q6E0
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
 RGD    
 Protein Sequence    
 Alignment    

-  Descriptions from all associated GenBank mRNAs
  AK147477 - Mus musculus cDNA, RIKEN full-length enriched library, clone:M5C1050C12 product:mitogen-activated protein kinase 8 interacting protein 3, full insert sequence.
AF178636 - Mus musculus JNK interacting protein-3a (Jip3) mRNA, complete cds.
BC060603 - Mus musculus mitogen-activated protein kinase 8 interacting protein 3, mRNA (cDNA clone MGC:79152 IMAGE:5706805), complete cds.
BC068312 - Mus musculus mitogen-activated protein kinase 8 interacting protein 3, mRNA (cDNA clone MGC:76677 IMAGE:30100914), complete cds.
BC065105 - Mus musculus mitogen-activated protein kinase 8 interacting protein 3, mRNA (cDNA clone MGC:85990 IMAGE:30356817), complete cds.
AB093282 - Mus musculus mRNA for mKIAA1066 protein.
AF178637 - Mus musculus JNK interacting protein-3b (Jip3) mRNA, complete cds.
AF262046 - Mus musculus sunday driver 2 (Syd2) mRNA, complete cds.
AB005662 - Mus musculus mRNA for JNK/SAPK-associated protein-1, complete cds.
AB043123 - Mus musculus Jsap1 mRNA for JNK/SAPK-associated protein 1b, complete cds.
AB043124 - Mus musculus Jsap1 mRNA for JNK/SAPK-associated protein 1c, complete cds.
AB043125 - Mus musculus Jsap1 mRNA for JNK/SAPK-associated protein 1d, complete cds.
AK134797 - Mus musculus adult male medulla oblongata cDNA, RIKEN full-length enriched library, clone:6330565K05 product:mitogen-activated protein kinase 8 interacting protein 3, full insert sequence.
BC004003 - Mus musculus mitogen-activated protein kinase 8 interacting protein 3, mRNA (cDNA clone IMAGE:3492743), partial cds.
AK043651 - Mus musculus 10 days neonate cortex cDNA, RIKEN full-length enriched library, clone:A830015H12 product:mitogen-activated protein kinase 8 interacting protein 3, full insert sequence.
AK050770 - Mus musculus 9 days embryo whole body cDNA, RIKEN full-length enriched library, clone:D030018G21 product:mitogen-activated protein kinase 8 interacting protein 3, full insert sequence.
AK039130 - Mus musculus adult male hypothalamus cDNA, RIKEN full-length enriched library, clone:A230101C01 product:mitogen-activated protein kinase 8 interacting protein 3, full insert sequence.
AK216552 - Mus musculus cDNA, clone:Y2G0138L24, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000024979, based on BLAT search.
AK183706 - Mus musculus cDNA, clone:Y0G0126N12, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000024979, based on BLAT search.
AK192589 - Mus musculus cDNA, clone:Y1G0109F16, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000024979, based on BLAT search.
AK035619 - Mus musculus adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530077J01 product:mitogen-activated protein kinase 8 interacting protein 3, full insert sequence.
AK182122 - Mus musculus cDNA, clone:Y0G0120O12, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000024979, based on BLAT search.
AK163208 - Mus musculus 7 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:A730099C06 product:mitogen-activated protein kinase 8 interacting protein 3, full insert sequence.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
mmu04010 - MAPK signaling pathway

-  Other Names for This Gene
  Alternate Gene Symbols: E9Q6E0, E9Q6E0_MOUSE, NM_001163450, uc008azd.1, uc008azd.2, uc008azd.3
UCSC ID: uc008azd.3
RefSeq Accession: NM_001163450
Protein: E9Q6E0 CCDS: CCDS37498.1, CCDS50024.1, CCDS50025.1, CCDS50026.1, CCDS50027.1, CCDS50028.1, CCDS50029.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.