Mouse Gene Myl12a (ENSMUST00000148960.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus myosin, light chain 12A, regulatory, non-sarcomeric (Myl12a), transcript variant 1, mRNA. (from RefSeq NM_026064)
Gencode Transcript: ENSMUST00000148960.7
Gencode Gene: ENSMUSG00000024048.15
Transcript (Including UTRs)
Position: mm10 chr17:70,993,656-71,002,554 Size: 8,899 Total Exon Count: 4 Strand: -
Coding Region
Position: mm10 chr17:70,994,612-70,996,880 Size: 2,269 Coding Exon Count: 3
Data last updated at UCSC: 2019-09-19
Sequence and Links to Tools and Databases
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR018248 - EF-hand
IPR011992 - EF-hand-like_dom
IPR018247 - EF_Hand_1_Ca_BS
IPR018249 - EF_HAND_2
IPR002048 - EF_hand_Ca-bd
Pfam Domains: PF00036 - EF hand
PF13202 - EF hand
PF13405 - EF-hand domain
PF13499 - EF-hand domain pair
PF13833 - EF-hand domain pair
SCOP Domains: 109998 - Triger factor/SurA peptide-binding domain-like
47473 - EF-hand
ModBase Predicted Comparative 3D Structure on Q6ZWQ9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK013776 - Mus musculus adult male hippocampus cDNA, RIKEN full-length enriched library, clone:2900073G15 product:myosin regulatory light chain A, smooth muscle homolog [Rattus norvegicus], full insert sequence.BC010265 - Mus musculus RIKEN cDNA 2900073G15 gene, mRNA (cDNA clone MGC:8089 IMAGE:3588394), complete cds.AK018348 - Mus musculus 12 days embryo female ovary cDNA, RIKEN full-length enriched library, clone:6620401G15 product:myosin regulatory light chain A, smooth muscle homolog [Rattus norvegicus], full insert sequence.BC020282 - Mus musculus RIKEN cDNA 2900073G15 gene, mRNA (cDNA clone IMAGE:3153484).BC029180 - Mus musculus RIKEN cDNA 2900073G15 gene, mRNA (cDNA clone MGC:35677 IMAGE:2599135), complete cds.BC006719 - Mus musculus RIKEN cDNA 2900073G15 gene, mRNA (cDNA clone IMAGE:3711075), partial cds.BC089050 - Mus musculus cDNA clone IMAGE:5328490, **** WARNING: chimeric clone ****.AK045160 - Mus musculus 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130042B20 product:myosin regulatory light chain A, smooth muscle homolog [Rattus norvegicus], full insert sequence.AK168016 - Mus musculus CRL-1722 L5178Y-R cDNA, RIKEN full-length enriched library, clone:I730047D20 product:Myosin regulatory light chain 2-A, smooth muscle isoform (Myosin RLC-A) homolog [Rattus norvegicus], full insert sequence.AK159151 - Mus musculus osteoclast-like cell cDNA, RIKEN full-length enriched library, clone:I420005I07 product:Myosin regulatory light chain 2-A, smooth muscle isoform (Myosin RLC-A) homolog [Rattus norvegicus], full insert sequence.AK167553 - Mus musculus 14 days pregnant adult female placenta cDNA, RIKEN full-length enriched library, clone:I530020L12 product:Myosin regulatory light chain 2-A, smooth muscle isoform (Myosin RLC-A) homolog [Rattus norvegicus], full insert sequence.AK151265 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830027H03 product:Myosin regulatory light chain 2-A, smooth muscle isoform (Myosin RLC-A) homolog [Rattus norvegicus], full insert sequence.AK028020 - Mus musculus 18-day embryo whole body cDNA, RIKEN full-length enriched library, clone:1190017I13 product:myosin regulatory light chain A, smooth muscle homolog [Rattus norvegicus], full insert sequence.LF249244 - JP 2014500723-A/56747: Polycomb-Associated Non-Coding RNAs.MA484821 - JP 2018138019-A/56747: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: mCG_5400, NM_026064, Q6ZWQ9, Q6ZWQ9_MOUSE, uc008dlw.1, uc008dlw.2UCSC ID: uc008dlw.2RefSeq Accession: NM_026064
Protein: Q6ZWQ9
CCDS: CCDS28955.1
Gene Model Information
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.