Mouse Gene Slc22a27 (ENSMUST00000075619.4) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus solute carrier family 22, member 27 (Slc22a27), transcript variant 1, mRNA. (from RefSeq NM_134256)
Gencode Transcript: ENSMUST00000075619.4
Gencode Gene: ENSMUSG00000067656.13
Transcript (Including UTRs)
   Position: mm10 chr19:7,864,388-7,966,027 Size: 101,640 Total Exon Count: 11 Strand: -
Coding Region
   Position: mm10 chr19:7,864,777-7,926,770 Size: 61,994 Coding Exon Count: 10 

Page IndexSequence and LinksPrimersRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:7,864,388-7,966,027)mRNA (may differ from genome)Protein (551 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsMGIPubMed
SOURCEUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -21.80107-0.204 Picture PostScript Text
3' UTR -80.00389-0.206 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR020846 - MFS_dom
IPR016196 - MFS_dom_general_subst_transpt
IPR005828 - Sub_transporter

Pfam Domains:
PF00083 - Sugar (and other) transporter
PF07690 - Major Facilitator Superfamily

SCOP Domains:
103473 - MFS general substrate transporter

ModBase Predicted Comparative 3D Structure on Q76M72
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005452 inorganic anion exchanger activity
GO:0015143 urate transmembrane transporter activity
GO:0015347 sodium-independent organic anion transmembrane transporter activity
GO:0022857 transmembrane transporter activity

Biological Process:
GO:0015698 inorganic anion transport
GO:0015747 urate transport
GO:0043252 sodium-independent organic anion transport
GO:0055085 transmembrane transport

Cellular Component:
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AB056443 - Mus musculus mOAT6 mRNA for organic anion transporter 6, complete cds.
AB056442 - Mus musculus OAT6RP mRNA for mOAT6-related protein, complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: AB056442, NM_134256, OAT6RP, Q76M72, Q76M72_MOUSE, uc008gls.1, uc008gls.2
UCSC ID: uc008gls.2
RefSeq Accession: NM_134256
Protein: Q76M72 CCDS: CCDS50380.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.