ID:LRC8A_MOUSE DESCRIPTION: RecName: Full=Leucine-rich repeat-containing protein 8A; FUNCTION: Involved in B-cell development. Required for the pro-B cell to pre-B cell transition. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). TISSUE SPECIFICITY: High levels detected in the bone marrow; lower levels found in peripheral blood cells. SIMILARITY: Contains 17 LRR (leucine-rich) repeats.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 52047 - RNI-like 52058 - L domain-like 52075 - Outer arm dynein light chain 1
ModBase Predicted Comparative 3D Structure on Q80WG5
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Protein Q80WG5 (Reactome details) participates in the following event(s):
R-MMU-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region R-MMU-5223345 Miscellaneous transport and binding events R-MMU-382551 Transport of small molecules
US Server
