Mouse Gene Dnm1 (ENSMUST00000091089.11) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus dynamin 1 (Dnm1), transcript variant 1, mRNA. (from RefSeq NM_010065) RefSeq Summary (NM_010065): This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein is a GTPase which is required for membrane recycling, including vesicle endocytosis in neurons. It may also be involved in cellular fission via association with microtubules and actin filaments. Mutations in this gene have been shown to cause seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]. Gencode Transcript: ENSMUST00000091089.11 Gencode Gene: ENSMUSG00000026825.17 Transcript (Including UTRs) Position: mm10 chr2:32,308,471-32,353,284 Size: 44,814 Total Exon Count: 21 Strand: - Coding Region Position: mm10 chr2:32,309,565-32,353,209 Size: 43,645 Coding Exon Count: 21
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P39053
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
KEGG - Kyoto Encyclopedia of Genes and Genomes mmu04144 - Endocytosis mmu04666 - Fc gamma R-mediated phagocytosis mmu04961 - Endocrine and other factor-regulated calcium reabsorption mmu05100 - Bacterial invasion of epithelial cells
BioCarta from NCI Cancer Genome Anatomy Project m_bArrestin-srcPathway - Roles of ¿-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling m_ndkDynaminPathway - Endocytotic role of NDK, Phosphins and Dynamin m_bArrestinPathway - ¿-arrestins in GPCR Desensitization m_barr-mapkPathway - Role of ¿-arrestins in the activation and targeting of MAP kinases
Reactome (by CSHL, EBI, and GO)
Protein P39053 (Reactome details) participates in the following event(s):
US Server
Sequence and Links to Tools and Databases 
