Mouse Gene Slc2a10 (ENSMUST00000029196.4) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus solute carrier family 2 (facilitated glucose transporter), member 10 (Slc2a10), mRNA. (from RefSeq NM_130451) RefSeq Summary (NM_130451): This gene encodes a class III facilitative glucose transporter. Mutations in the related gene in human are associated with arterial tortuosity syndrome. [provided by RefSeq, Dec 2013]. Gencode Transcript: ENSMUST00000029196.4 Gencode Gene: ENSMUSG00000027661.4 Transcript (Including UTRs) Position: mm10 chr2:165,503,787-165,519,917 Size: 16,131 Total Exon Count: 5 Strand: + Coding Region Position: mm10 chr2:165,504,045-165,518,242 Size: 14,198 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 103473 - MFS general substrate transporter
ModBase Predicted Comparative 3D Structure on Q8VHD6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0008643 carbohydrate transport GO:0046323 glucose import GO:0055085 transmembrane transport GO:1902600 hydrogen ion transmembrane transport GO:1904659 glucose transmembrane transport
AK052156 - Mus musculus 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330001H08 product:solute carrier family 2 (facilitated glucose transporter), member 10, full insert sequence. BC137917 - Mus musculus solute carrier family 2 (facilitated glucose transporter), member 10, mRNA (cDNA clone MGC:169541 IMAGE:8860936), complete cds. BC137920 - Mus musculus solute carrier family 2 (facilitated glucose transporter), member 10, mRNA (cDNA clone MGC:169544 IMAGE:8860939), complete cds. AY029579 - Mus musculus glucose transporter 10 mRNA, complete cds.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q8VHD6 (Reactome details) participates in the following event(s):
R-MMU-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol R-MMU-189200 Cellular hexose transport R-MMU-425407 SLC-mediated transmembrane transport R-MMU-382551 Transport of small molecules