Mouse Gene Mynn (ENSMUST00000192715.5) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus myoneurin (Mynn), transcript variant 1, mRNA. (from RefSeq NM_030557)
Gencode Transcript: ENSMUST00000192715.5
Gencode Gene: ENSMUSG00000037730.13
Transcript (Including UTRs)
   Position: mm10 chr3:30,602,065-30,619,873 Size: 17,809 Total Exon Count: 8 Strand: +
Coding Region
   Position: mm10 chr3:30,603,535-30,616,813 Size: 13,279 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:30,602,065-30,619,873)mRNA (may differ from genome)Protein (610 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: MYNN_MOUSE
DESCRIPTION: RecName: Full=Myoneurin;
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Mainly expressed in the neuromuscular system. Located in and around synaptic myonuclei in adult muscle. Expression is dysregulated after nerve injury. Also found in the cerebellum, testis, heart, brain and liver.
DEVELOPMENTAL STAGE: Expression is developmentally regulated in muscle and is associated with neuromuscular junctions during the late embryonic period.
SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.
SIMILARITY: Contains 1 BTB (POZ) domain.
SIMILARITY: Contains 8 C2H2-type zinc fingers.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -250.20662-0.378 Picture PostScript Text
3' UTR -740.443060-0.242 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000210 - BTB/POZ-like
IPR011333 - BTB/POZ_fold
IPR013069 - BTB_POZ
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00096 - Zinc finger, C2H2 type
PF00651 - BTB/POZ domain
PF12874 - Zinc-finger of C2H2 type
PF13894 - C2H2-type zinc finger
PF13912 - C2H2-type zinc finger

SCOP Domains:
54695 - POZ domain
57667 - beta-beta-alpha zinc fingers
57716 - Glucocorticoid receptor-like (DNA-binding domain)
82919 - Zn-finger domain of Sec23/24
57783 - Zinc beta-ribbon
57802 - Rubredoxin-like
57889 - Cysteine-rich domain
57903 - FYVE/PHD zinc finger

ModBase Predicted Comparative 3D Structure on Q99MD8
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGDEnsembl   
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:1990830 cellular response to leukemia inhibitory factor

Cellular Component:
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  BC065084 - Mus musculus myoneurin, mRNA (cDNA clone MGC:86109 IMAGE:6848601), complete cds.
AK013445 - Mus musculus 10, 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2810486O05 product:myoneurin, full insert sequence.
AK030898 - Mus musculus adult male thymus cDNA, RIKEN full-length enriched library, clone:5830450I21 product:myoneurin, full insert sequence.
AK147959 - Mus musculus melanocyte cDNA, RIKEN full-length enriched library, clone:G270118K08 product:myoneurin, full insert sequence.
AK135273 - Mus musculus 12 days embryo male wolffian duct includes surrounding region cDNA, RIKEN full-length enriched library, clone:6720450M06 product:myoneurin, full insert sequence.
AK136107 - Mus musculus in vitro fertilized eggs cDNA, RIKEN full-length enriched library, clone:7420457K05 product:myoneurin, full insert sequence.
AK014315 - Mus musculus 14, 17 days embryo head cDNA, RIKEN full-length enriched library, clone:3222401C14 product:myoneurin, full insert sequence.
BC007477 - Mus musculus myoneurin, mRNA (cDNA clone IMAGE:3592663), complete cds.
AK019238 - Mus musculus 10, 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2810011C24 product:myoneurin, full insert sequence.
AK163261 - Mus musculus 2 cells egg cDNA, RIKEN full-length enriched library, clone:B020007C19 product:myoneurin, full insert sequence.
AK163264 - Mus musculus 2 cells egg cDNA, RIKEN full-length enriched library, clone:B020007E19 product:myoneurin, full insert sequence.
AK029657 - Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4930431K05 product:myoneurin, full insert sequence.
AF349561 - Mus musculus myoneurin mRNA, complete cds.
AB010307 - Mus musculus mRNA for mszf2, partial cds.

-  Other Names for This Gene
  Alternate Gene Symbols: MYNN_MOUSE, NM_030557, Q6P1G7, Q8BT55, Q922I4, Q99MD8, Q9CSA0, Q9CXJ8, uc008oux.1, uc008oux.2, uc008oux.3
UCSC ID: uc008oux.3
RefSeq Accession: NM_030557
Protein: Q99MD8 (aka MYNN_MOUSE)
CCDS: CCDS17284.1, CCDS79891.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.