Mouse Gene Pgrmc2 (ENSMUST00000058578.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus progesterone receptor membrane component 2 (Pgrmc2), mRNA. (from RefSeq NM_027558)
Gencode Transcript: ENSMUST00000058578.7
Gencode Gene: ENSMUSG00000049940.7
Transcript (Including UTRs)
Position: mm10 chr3:41,066,326-41,083,046 Size: 16,721 Total Exon Count: 3 Strand: -
Coding Region
Position: mm10 chr3:41,068,627-41,082,994 Size: 14,368 Coding Exon Count: 3
Data last updated at UCSC: 2019-09-19
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: PGRC2_MOUSE
DESCRIPTION: RecName: Full=Membrane-associated progesterone receptor component 2;
FUNCTION: Receptor for steroids (Potential).SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).DOMAIN: The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 131 and 155 (By similarity).SIMILARITY: Belongs to the cytochrome b5 family. MAPR subfamily.SIMILARITY: Contains 1 cytochrome b5 heme-binding domain.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001199 - Cyt_B5
Pfam Domains: PF00173 - Cytochrome b5-like Heme/Steroid binding domain
SCOP Domains: 55856 - Cytochrome b5-like heme/steroid binding domain
ModBase Predicted Comparative 3D Structure on Q80UU9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC044759 - Mus musculus progesterone receptor membrane component 2, mRNA (cDNA clone IMAGE:5061936), partial cds.AX775753 - Sequence 23 from Patent WO03048202.AK140064 - Mus musculus adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230117D02 product:progesterone receptor membrane component 2, full insert sequence.AK014543 - Mus musculus 0 day neonate skin cDNA, RIKEN full-length enriched library, clone:4631434O19 product:MEMBRANE ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 2 (PROGESTERONE MEMBRANE BINDING PROTEIN) (STEROID RECEPTOR PROTEIN DG6) homolog [Homo sapiens], full insert sequence.AK184626 - Mus musculus cDNA, clone:Y0G0130O13, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000058578, based on BLAT search.AK165560 - Mus musculus brain CRL-1443 BC3H1 cDNA, RIKEN full-length enriched library, clone:G430007N18 product:progesterone receptor membrane component 2, full insert sequence.AK181500 - Mus musculus cDNA, clone:Y0G0118F18, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000058578, based on BLAT search.AK211355 - Mus musculus cDNA, clone:Y2G0121H19, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000058578, based on BLAT search.AK199826 - Mus musculus cDNA, clone:Y1G0132I02, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000058578, based on BLAT search.AK184727 - Mus musculus cDNA, clone:Y0G0131F03, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000058578, based on BLAT search.
Other Names for This Gene
Alternate Gene Symbols: NM_027558, PGRC2_MOUSE, Q80UU9, uc008pce.1, uc008pce.2UCSC ID: uc008pce.2RefSeq Accession: NM_027558
Protein: Q80UU9
(aka PGRC2_MOUSE)
CCDS: CCDS50899.1
Gene Model Information
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.