The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q80VL1
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK012596 - Mus musculus 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2700091C21 product:similar to PUTATIVE RNA BINDING PROTEIN [Homo sapiens], full insert sequence. BC057030 - Mus musculus tudor and KH domain containing protein, mRNA (cDNA clone MGC:67203 IMAGE:6833743), complete cds. BC031886 - Mus musculus tudor and KH domain containing protein, mRNA (cDNA clone IMAGE:5365523), with apparent retained intron. BC049363 - Mus musculus tudor and KH domain containing protein, mRNA (cDNA clone MGC:57093 IMAGE:6490411), complete cds. AK018134 - Mus musculus adult male medulla oblongata cDNA, RIKEN full-length enriched library, clone:6330407D06 product:unclassifiable, full insert sequence.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q80VL1 (Reactome details) participates in the following event(s):
R-MMU-5615685 Complexed Piwil1 binds pre-piRNA R-MMU-5629239 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in 4xMeR-Piwil1:piRNA:Tdrd6:Tdrkh R-MMU-5629230 Henmt1 methylates 2' hydroxyl at 3' end of piRNA in MeR-Piwil4:piRNA:Tdrd9:Mael:Tdrkh