ID:HINT2_MOUSE DESCRIPTION: RecName: Full=Histidine triad nucleotide-binding protein 2, mitochondrial; Short=HINT-2; EC=3.-.-.-; AltName: Full=HINT-3; Flags: Precursor; FUNCTION: Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity (By similarity). SUBCELLULAR LOCATION: Mitochondrion (By similarity). DOMAIN: The histidine triad, also called HIT motif, forms part of the binding loop for the alpha-phosphate of purine mononucleotide. SIMILARITY: Belongs to the HINT family. SIMILARITY: Contains 1 HIT domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9D0S9
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006629 lipid metabolic process GO:0006694 steroid biosynthetic process GO:0006915 apoptotic process GO:0016042 lipid catabolic process GO:2000757 negative regulation of peptidyl-lysine acetylation
US Server
