Mouse Gene 2210010C04Rik (ENSMUST00000031931.5) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus RIKEN cDNA 2210010C04 gene (2210010C04Rik), mRNA. (from RefSeq NM_023333)
Gencode Transcript: ENSMUST00000031931.5
Gencode Gene: ENSMUSG00000029882.5
Transcript (Including UTRs)
   Position: mm10 chr6:41,030,268-41,035,509 Size: 5,242 Total Exon Count: 5 Strand: -
Coding Region
   Position: mm10 chr6:41,031,635-41,035,478 Size: 3,844 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsPrimersRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6:41,030,268-41,035,509)mRNA (may differ from genome)Protein (247 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: Q9CPN9_MOUSE
DESCRIPTION: SubName: Full=Protein 2210010C04Rik; SubName: Full=RIKEN cDNA 2210010C04, isoform CRA_b; SubName: Full=Trypsinogen 7;
SIMILARITY: Belongs to the peptidase S1 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -6.1031-0.197 Picture PostScript Text
3' UTR -296.821367-0.217 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR009003 - Pept_cys/ser_Trypsin-like
IPR018114 - Peptidase_S1/S6_AS
IPR001254 - Peptidase_S1_S6
IPR001314 - Peptidase_S1A

Pfam Domains:
PF00089 - Trypsin

SCOP Domains:
50494 - Trypsin-like serine proteases

ModBase Predicted Comparative 3D Structure on Q9CPN9
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
      
      
 RGDEnsembl   
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0004252 serine-type endopeptidase activity
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity

Biological Process:
GO:0006508 proteolysis

Cellular Component:
GO:0005615 extracellular space


-  Descriptions from all associated GenBank mRNAs
  AK008695 - Mus musculus adult male stomach cDNA, RIKEN full-length enriched library, clone:2210010C04 product:TRYPSIN III, CATIONIC PRECURSOR (EC 3.4.21.4) (PRETRYPSINOGEN III) homolog [Rattus norvegicus], full insert sequence.
AK007943 - Mus musculus 10 day old male pancreas cDNA, RIKEN full-length enriched library, clone:1810063E12 product:inferred: trypsinogen 7, full insert sequence.
AK008460 - Mus musculus adult male small intestine cDNA, RIKEN full-length enriched library, clone:2010206B10 product:TRYPSIN III, CATIONIC PRECURSOR (EC 3.4.21.4) (PRETRYPSINOGEN III) homolog [Rattus norvegicus], full insert sequence.
BC061093 - Mus musculus RIKEN cDNA 2210010C04 gene, mRNA (cDNA clone MGC:74211 IMAGE:30306963), complete cds.
AK007775 - Mus musculus 10 day old male pancreas cDNA, RIKEN full-length enriched library, clone:1810044H15 product:RIKEN cDNA 2210010C04 gene, full insert sequence.
AK007773 - Mus musculus 10 day old male pancreas cDNA, RIKEN full-length enriched library, clone:1810044F08 product:TRYPSIN III, CATIONIC PRECURSOR (EC 3.4.21.4) (PRETRYPSINOGEN III) homolog [Rattus norvegicus], full insert sequence.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
mmu04080 - Neuroactive ligand-receptor interaction
mmu04972 - Pancreatic secretion
mmu04974 - Protein digestion and absorption

-  Other Names for This Gene
  Alternate Gene Symbols: mCG_15095, NM_023333, Q9CPN9, Q9CPN9_MOUSE, trypsinogen, uc009bno.1
UCSC ID: uc009bno.1
RefSeq Accession: NM_023333
Protein: Q9CPN9 CCDS: CCDS20043.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.