Mouse Gene Capg (uc009cis.1) Description and Page Index
  Description: macrophage-capping protein isoform 1
Transcript (Including UTRs)
   Position: mm9 chr6:72,494,433-72,512,974 Size: 18,542 Total Exon Count: 10 Strand: +
Coding Region
   Position: mm9 chr6:72,505,280-72,512,869 Size: 7,590 Coding Exon Count: 9 

Page IndexSequence and LinksCTDMicroarray ExpressionRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2011-03-02

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr6:72,494,433-72,512,974)mRNA (may differ from genome)Protein (349 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAllen Brain Atlas
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkMGIPubMedStanford SOURCEUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from GNF1M Mouse Chip

    
     
      
       
     
    
   
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Absolute

Rinn et. al Sex Gene Expression Data on MOE430A Chip

        
Ratios
        
Absolute

Affymetrix All Exon Microarrays

           
Ratios

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -4.7041-0.115 Picture PostScript Text
3' UTR -29.60105-0.282 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007122 - Gelsolin
IPR007123 - Gelsolin_dom

Pfam Domains:
PF00626 - Gelsolin repeat

SCOP Domains:
55753 - Actin depolymerizing proteins
82754 - C-terminal, gelsolin-like domain of Sec23/24

ModBase Predicted Comparative 3D Structure on Q99LB4
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0019904 protein domain specific binding
GO:0044877 macromolecular complex binding
GO:0051015 actin filament binding

Biological Process:
GO:0051016 barbed-end actin filament capping

Cellular Component:
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0072686 mitotic spindle
GO:0090543 Flemming body


-  Descriptions from all associated GenBank mRNAs
  AK165153 - Mus musculus 10 days neonate olfactory brain cDNA, RIKEN full-length enriched library, clone:E530115O13 product:capping protein (actin filament), gelsolin-like, full insert sequence.
AK159577 - Mus musculus osteoclast-like cell cDNA, RIKEN full-length enriched library, clone:I420024N07 product:capping protein (actin filament), gelsolin-like, full insert sequence.
AK159736 - Mus musculus osteoclast-like cell cDNA, RIKEN full-length enriched library, clone:I420029F14 product:capping protein (actin filament), gelsolin-like, full insert sequence.
X54511 - M.musculus mbh1 gene for Myc basic motif homologue-1 (mbh1).
AK146622 - Mus musculus 17 days pregnant adult female amnion cDNA, RIKEN full-length enriched library, clone:I920035K17 product:capping protein (actin filament), gelsolin-like, full insert sequence.
AK152818 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830086L21 product:capping protein (actin filament), gelsolin-like, full insert sequence.
BC003480 - Mus musculus capping protein (actin filament), gelsolin-like, mRNA (cDNA clone MGC:6242 IMAGE:2811050), complete cds.
AK149857 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:G530023L14 product:capping protein (actin filament), gelsolin-like, full insert sequence.
BC023101 - Mus musculus capping protein (actin filament), gelsolin-like, mRNA (cDNA clone MGC:28153 IMAGE:3983574), complete cds.
AK165586 - Mus musculus bladder RCB-0544 MBT-2 cDNA, RIKEN full-length enriched library, clone:G430030G08 product:capping protein (actin filament), gelsolin-like, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: mCG_129296, NM_007599, NP_031625, Q99LB4, Q99LB4_MOUSE
UCSC ID: uc009cis.1
RefSeq Accession: NM_007599
Protein: Q99LB4 CCDS: CCDS39516.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_007599.3
exon count: 10CDS single in 3' UTR: no RNA size: 1194
ORF size: 1050CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2298.50frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.