Mouse Gene Rps9 (ENSMUST00000006496.14) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus ribosomal protein S9 (Rps9), mRNA. (from RefSeq NM_029767)
Gencode Transcript: ENSMUST00000006496.14
Gencode Gene: ENSMUSG00000006333.14
Transcript (Including UTRs)
   Position: mm10 chr7:3,703,993-3,706,897 Size: 2,905 Total Exon Count: 5 Strand: +
Coding Region
   Position: mm10 chr7:3,704,352-3,706,828 Size: 2,477 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsPathwaysOther Names
Model InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:3,703,993-3,706,897)mRNA (may differ from genome)Protein (194 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedReactomeSOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: RS9_MOUSE
DESCRIPTION: RecName: Full=40S ribosomal protein S9;
SUBUNIT: Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity).
SIMILARITY: Belongs to the ribosomal protein S4P family.
SIMILARITY: Contains 1 S4 RNA-binding domain.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -28.8097-0.297 Picture PostScript Text
3' UTR -13.9069-0.201 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR022801 - Ribosomal_S4/S9
IPR005710 - Ribosomal_S4/S9_euk/arc
IPR001912 - Ribosomal_S4/S9_N
IPR018079 - Ribosomal_S4_CS
IPR002942 - S4_RNA-bd

Pfam Domains:
PF00163 - Ribosomal protein S4/S9 N-terminal domain
PF01479 - S4 domain

SCOP Domains:
55174 - Alpha-L RNA-binding motif

ModBase Predicted Comparative 3D Structure on Q6ZWN5
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0045182 translation regulator activity
GO:1990932 5.8S rRNA binding

Biological Process:
GO:0006412 translation
GO:0008284 positive regulation of cell proliferation
GO:0045903 positive regulation of translational fidelity

Cellular Component:
GO:0005622 intracellular
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex


-  Descriptions from all associated GenBank mRNAs
  AK081889 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130085C18 product:SIMILAR TO RIBOSOMAL PROTEIN S9 (UNKNOWN) (PROTEIN FOR MGC:14341) (PROTEIN FOR MGC:2458) (PROTEIN FOR MGC:4138) homolog [Homo sapiens], full insert sequence.
AK013903 - Mus musculus 12 days embryo head cDNA, RIKEN full-length enriched library, clone:3010033P07 product:40S RIBOSOMAL PROTEIN S9 (FRAGMENT) homolog [Sus scrofa], full insert sequence.
AK151621 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830032E16 product:40S ribosomal protein S9 homolog [Homo sapiens], full insert sequence.
AK150988 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830019H17 product:40S ribosomal protein S9 homolog [Homo sapiens], full insert sequence.
AK050591 - Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:C920007P20 product:SIMILAR TO RIBOSOMAL PROTEIN S9 (UNKNOWN) (PROTEIN FOR MGC:14341) (PROTEIN FOR MGC:2458) (PROTEIN FOR MGC:4138) homolog [Homo sapiens], full insert sequence.
AK151029 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830020L13 product:40S ribosomal protein S9 homolog [Homo sapiens], full insert sequence.
AK150800 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830015I10 product:40S ribosomal protein S9 homolog [Homo sapiens], full insert sequence.
BC031746 - Mus musculus ribosomal protein S9, mRNA (cDNA clone MGC:19433 IMAGE:3494314), complete cds.
BC012491 - Mus musculus ribosomal protein S9, mRNA (cDNA clone IMAGE:4500773), partial cds.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
mmu03010 - Ribosome

Reactome (by CSHL, EBI, and GO)

Protein Q6ZWN5 (Reactome details) participates in the following event(s):

R-MMU-72676 eIF3 and eIF1A bind to the 40S subunit
R-MMU-157849 Formation of translation initiation complexes containing mRNA that does not circularize
R-MMU-72691 Formation of the 43S pre-initiation complex
R-MMU-72621 Ribosomal scanning
R-MMU-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA
R-MMU-72689 Formation of a pool of free 40S subunits
R-MMU-72649 Translation initiation complex formation
R-MMU-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-MMU-72737 Cap-dependent Translation Initiation
R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-MMU-72702 Ribosomal scanning and start codon recognition
R-MMU-156827 L13a-mediated translation
R-MMU-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
R-MMU-72613 Eukaryotic Translation Initiation
R-MMU-8868773 rRNA processing in the nucleus and cytosol
R-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
R-MMU-72766 Translation
R-MMU-72312 rRNA processing
R-MMU-927802 Nonsense-Mediated Decay (NMD)
R-MMU-392499 Metabolism of proteins
R-MMU-8953854 Metabolism of RNA

-  Other Names for This Gene
  Alternate Gene Symbols: NM_029767, Q3UBF1, Q6ZWN5, Q8K2D1, RS9_MOUSE, uc009ewa.1, uc009ewa.2
UCSC ID: uc009ewa.2
RefSeq Accession: NM_029767
Protein: Q6ZWN5 (aka RS9_MOUSE)
CCDS: CCDS20726.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.