ID:TIM50_MOUSE DESCRIPTION: RecName: Full=Mitochondrial import inner membrane translocase subunit TIM50; Flags: Precursor; FUNCTION: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (By similarity). SUBUNIT: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50. Interacts directly with TIMM23 (By similarity). SUBCELLULAR LOCATION: Mitochondrion inner membrane; Single-pass membrane protein (By similarity). SIMILARITY: Belongs to the TIM50 family. SIMILARITY: Contains 1 FCP1 homology domain. SEQUENCE CAUTION: Sequence=AAH10303.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9D880
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0001836 release of cytochrome c from mitochondria GO:0006470 protein dephosphorylation GO:0007006 mitochondrial membrane organization GO:0015031 protein transport GO:0030150 protein import into mitochondrial matrix GO:0035335 peptidyl-tyrosine dephosphorylation
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