Mouse Gene Klk1b22 (ENSMUST00000077528.6) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus kallikrein 1-related peptidase b22 (Klk1b22), mRNA. (from RefSeq NM_010114) RefSeq Summary (NM_010114): This gene encodes the beta subunit of the 7S nerve growth factor (NGF) complex that is essential for the differentiation and survival of distinct populations of neurons in both the central and the peripheral nervous systems. The encoded preproprotein undergoes proteolytic processing to generate a functional, mature peptide. This gene is located in a cluster of several related kallikrein genes on chromosome 7. [provided by RefSeq, Feb 2016]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Gencode Transcript: ENSMUST00000077528.6 Gencode Gene: ENSMUSG00000060177.6 Transcript (Including UTRs) Position: mm10 chr7:44,112,673-44,116,922 Size: 4,250 Total Exon Count: 5 Strand: + Coding Region Position: mm10 chr7:44,112,702-44,116,876 Size: 4,175 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q540N3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Human
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Gene Ontology (GO) Annotations with Structured Vocabulary