Mouse Gene Crym (ENSMUST00000033198.5) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus crystallin, mu (Crym), mRNA. (from RefSeq NM_016669)
Gencode Transcript: ENSMUST00000033198.5
Gencode Gene: ENSMUSG00000030905.5
Transcript (Including UTRs)
   Position: mm10 chr7:120,186,380-120,202,111 Size: 15,732 Total Exon Count: 8 Strand: -
Coding Region
   Position: mm10 chr7:120,186,634-120,201,924 Size: 15,291 Coding Exon Count: 8 

Page IndexSequence and LinksPrimersCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:120,186,380-120,202,111)mRNA (may differ from genome)Protein (313 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKBWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -88.20187-0.472 Picture PostScript Text
3' UTR -62.40254-0.246 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR016040 - NAD(P)-bd_dom
IPR003462 - ODC_Mu_crystall

Pfam Domains:
PF01488 - Shikimate / quinate 5-dehydrogenase
PF02423 - Ornithine cyclodeaminase/mu-crystallin family

SCOP Domains:
49899 - Concanavalin A-like lectins/glucanases
51735 - NAD(P)-binding Rossmann-fold domains
53671 - Aspartate/ornithine carbamoyltransferase

ModBase Predicted Comparative 3D Structure on Q3UPX0
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserNo orthologNo ortholog
Gene Details    Gene Details
Gene Sorter    Gene Sorter
GenBankRGDEnsemblEnsembl SGD
Protein SequenceProtein Sequence Protein Sequence  
AlignmentAlignment Alignment  

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003714 transcription corepressor activity
GO:0042562 hormone binding
GO:0042803 protein homodimerization activity
GO:0050661 NADP binding
GO:0070324 thyroid hormone binding

Biological Process:
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0007605 sensory perception of sound
GO:0042403 thyroid hormone metabolic process
GO:0070327 thyroid hormone transport

Cellular Component:
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol


-  Descriptions from all associated GenBank mRNAs
  AF039391 - Mus musculus mu-crystallin (Crym) mRNA, complete cds.
AK143116 - Mus musculus 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130107I12 product:crystallin, mu, full insert sequence.
BC045159 - Mus musculus crystallin, mu, mRNA (cDNA clone MGC:54583 IMAGE:6492374), complete cds.
AK138422 - Mus musculus adult male hypothalamus cDNA, RIKEN full-length enriched library, clone:A230099G02 product:crystallin, mu, full insert sequence.
AK163781 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130020P17 product:crystallin, mu, full insert sequence.
AK163801 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130037G07 product:crystallin, mu, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: mCG_7593, NM_016669, Q3UPX0, Q3UPX0_MOUSE, uc009jmk.1, uc009jmk.2
UCSC ID: uc009jmk.2
RefSeq Accession: NM_016669
Protein: Q3UPX0 CCDS: CCDS21794.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.