Mouse Gene Zfp771 (ENSMUST00000052509.5) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus zinc finger protein 771 (Zfp771), transcript variant 1, mRNA. (from RefSeq NM_177362)
Gencode Transcript: ENSMUST00000052509.5
Gencode Gene: ENSMUSG00000054716.4
Transcript (Including UTRs)
   Position: mm10 chr7:127,244,274-127,254,803 Size: 10,530 Total Exon Count: 3 Strand: +
Coding Region
   Position: mm10 chr7:127,244,994-127,254,617 Size: 9,624 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsPrimersRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:127,244,274-127,254,803)mRNA (may differ from genome)Protein (317 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsMGIPubMed
ReactomeSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: ZN771_MOUSE
DESCRIPTION: RecName: Full=Zinc finger protein 771;
FUNCTION: May be involved in transcriptional regulation.
SUBCELLULAR LOCATION: Nucleus (Probable).
SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.
SIMILARITY: Contains 8 C2H2-type zinc fingers.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -175.70344-0.511 Picture PostScript Text
3' UTR -66.60186-0.358 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00096 - Zinc finger, C2H2 type
PF13894 - C2H2-type zinc finger
PF13912 - C2H2-type zinc finger
PF13913 - zinc-finger of a C2HC-type

SCOP Domains:
54862 - 4Fe-4S ferredoxins
144020 - FdhE-like
57667 - beta-beta-alpha zinc fingers
57716 - Glucocorticoid receptor-like (DNA-binding domain)
57783 - Zinc beta-ribbon
57802 - Rubredoxin-like
63393 - RNA polymerase subunits
57889 - Cysteine-rich domain
57903 - FYVE/PHD zinc finger
161219 - CHY zinc finger-like

ModBase Predicted Comparative 3D Structure on Q8BJ90
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process

Cellular Component:
GO:0005634 nucleus
GO:0005730 nucleolus


-  Descriptions from all associated GenBank mRNAs
  AK090240 - Mus musculus 0 day neonate cortex cDNA, RIKEN full-length enriched library, clone:G630024C07 product:hypothetical Zinc finger, C2H2 type containing protein, full insert sequence.
AK159461 - Mus musculus osteoclast-like cell cDNA, RIKEN full-length enriched library, clone:I420020H24 product:melanophilin, full insert sequence.
BC139048 - Mus musculus zinc finger protein 771, mRNA (cDNA clone MGC:170675 IMAGE:8862070), complete cds.
BC139049 - Mus musculus zinc finger protein 771, mRNA (cDNA clone MGC:170676 IMAGE:8862071), complete cds.
BC145524 - Mus musculus zinc finger protein 771, mRNA (cDNA clone MGC:179095 IMAGE:9054087), complete cds.
BC052091 - Mus musculus zinc finger protein 771, mRNA (cDNA clone IMAGE:5693350), with apparent retained intron.
BC062882 - Mus musculus zinc finger protein 771, mRNA (cDNA clone IMAGE:5693350), partial cds.

-  Biochemical and Signaling Pathways
  Reactome (by CSHL, EBI, and GO)

Protein Q8BJ90 (Reactome details) participates in the following event(s):

R-MMU-975040 KRAB-ZNF / KAP Interaction
R-MMU-212436 Generic Transcription Pathway
R-MMU-73857 RNA Polymerase II Transcription
R-MMU-74160 Gene expression (Transcription)

-  Other Names for This Gene
  Alternate Gene Symbols: B2RSX6, NM_177362, Q6P5I0, Q8BJ90, uc009juv.1, uc009juv.2, ZN771_MOUSE, Znf771
UCSC ID: uc009juv.2
RefSeq Accession: NM_177362
Protein: Q8BJ90 (aka ZN771_MOUSE)
CCDS: CCDS21861.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.