Mouse Gene Zbtb44 (ENSMUST00000216649.1) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus zinc finger and BTB domain containing 44 (Zbtb44), transcript variant b, mRNA. (from RefSeq NM_172765)
Gencode Transcript: ENSMUST00000216649.1
Gencode Gene: ENSMUSG00000047412.16
Transcript (Including UTRs)
   Position: mm10 chr9:31,030,644-31,070,233 Size: 39,590 Total Exon Count: 6 Strand: +
Coding Region
   Position: mm10 chr9:31,053,296-31,068,755 Size: 15,460 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:31,030,644-31,070,233)mRNA (may differ from genome)Protein (435 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: ZBT44_MOUSE
DESCRIPTION: RecName: Full=Zinc finger and BTB domain-containing protein 44; AltName: Full=BTB/POZ domain-containing protein 15;
SUBCELLULAR LOCATION: Nucleus (By similarity).
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity).
SIMILARITY: Contains 1 BTB (POZ) domain.
SIMILARITY: Contains 2 C2H2-type zinc fingers.
SEQUENCE CAUTION: Sequence=BAC29628.1; Type=Erroneous termination; Positions=348; Note=Translated as Glu;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • C532162 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine
  • C049584 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
  • C028451 3,4,3',4'-tetrachlorobiphenyl
  • D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
  • D000082 Acetaminophen
  • D003993 Dibutyl Phthalate
  • D004041 Dietary Fats
  • D004237 Diuron
  • D007213 Indomethacin
  • D007545 Isoproterenol
          more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -162.90371-0.439 Picture PostScript Text
3' UTR -401.801478-0.272 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000210 - BTB/POZ-like
IPR011333 - BTB/POZ_fold
IPR013069 - BTB_POZ
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00651 - BTB/POZ domain
PF12874 - Zinc-finger of C2H2 type
PF13894 - C2H2-type zinc finger
PF13912 - C2H2-type zinc finger

SCOP Domains:
54695 - POZ domain
57667 - beta-beta-alpha zinc fingers
57783 - Zinc beta-ribbon

ModBase Predicted Comparative 3D Structure on Q8R0A2
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process

Cellular Component:
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  AK036895 - Mus musculus adult female vagina cDNA, RIKEN full-length enriched library, clone:9930022E12 product:hypothetical BTB/POZ domain containing protein, full insert sequence.
BC027138 - Mus musculus zinc finger and BTB domain containing 44, mRNA (cDNA clone IMAGE:5361486), **** WARNING: chimeric clone ****.
BC037671 - Mus musculus BTB (POZ) domain containing 15, mRNA (cDNA clone IMAGE:4486273).
AK157610 - Mus musculus activated spleen cDNA, RIKEN full-length enriched library, clone:F830226L10 product:unclassifiable, full insert sequence.
AK162427 - Mus musculus 12 days embryo embryonic body between diaphragm region and neck cDNA, RIKEN full-length enriched library, clone:9430018H05 product:hypothetical Zn-finger, C2H2 type/Zinc finger C2H2 type domain profile containing protein, full insert sequence.
DQ724668 - Mus musculus piRNA piR-139990, complete sequence.
AK020046 - Mus musculus 13 days embryo male testis cDNA, RIKEN full-length enriched library, clone:6030404E16 product:unclassifiable, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: Btbd15, NM_172765, Q8CB31, Q8R0A2, uc009ord.1, uc009ord.2, uc009ord.3, ZBT44_MOUSE
UCSC ID: uc009ord.3
RefSeq Accession: NM_172765
Protein: Q8R0A2 (aka ZBT44_MOUSE)
CCDS: CCDS40568.1, CCDS52747.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.