ID:JAML1_MOUSE DESCRIPTION: RecName: Full=Junctional adhesion molecule-like; AltName: Full=Dendritic cell-specific protein CREA7; Short=mCrea7; Flags: Precursor; FUNCTION: May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells (By similarity). SUBUNIT: Interacts with CXADR. SUBCELLULAR LOCATION: Cell junction (By similarity). Cell membrane; Single-pass type I membrane protein (By similarity). Note=Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN (By similarity). DOMAIN: The Ig-like V-type domain 2 mediates interaction with CXADR (By similarity). SIMILARITY: Belongs to the immunoglobulin superfamily. SIMILARITY: Contains 2 Ig-like V-type (immunoglobulin-like) domains.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q80UL9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
