Mouse Gene Car5b (ENSMUST00000033739.4) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus carbonic anhydrase 5b, mitochondrial (Car5b), mRNA. (from RefSeq NM_181315)
Gencode Transcript: ENSMUST00000033739.4
Gencode Gene: ENSMUSG00000031373.4
Transcript (Including UTRs)
Position: mm10 chrX:163,976,822-164,027,997 Size: 51,176 Total Exon Count: 8 Strand: -
Coding Region
Position: mm10 chrX:163,979,191-164,014,944 Size: 35,754 Coding Exon Count: 7
Data last updated at UCSC: 2019-09-19
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CAH5B_MOUSE
DESCRIPTION: RecName: Full=Carbonic anhydrase 5B, mitochondrial; EC=4.2.1.1; AltName: Full=Carbonate dehydratase VB; AltName: Full=Carbonic anhydrase VB; Short=CA-VB; Flags: Precursor;
FUNCTION: Reversible hydration of carbon dioxide.CATALYTIC ACTIVITY: H(2)CO(3) = CO(2) + H(2)O.COFACTOR: Zinc (By similarity).SUBCELLULAR LOCATION: Mitochondrion.SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
Primer design for this transcript
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR018437 - CA-V_mt
IPR001148 - Carbonic_anhydrase_a
IPR023561 - Carbonic_anhydrase_a-class
IPR018338 - Carbonic_anhydrase_a-class_CS
Pfam Domains: PF00194 - Eukaryotic-type carbonic anhydrase
SCOP Domains: 51069 - Carbonic anhydrase
ModBase Predicted Comparative 3D Structure on Q9QZA0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK041253 - Mus musculus adult male aorta and vein cDNA, RIKEN full-length enriched library, clone:A530094K10 product:unclassifiable, full insert sequence.AK163076 - Mus musculus adult male aorta and vein cDNA, RIKEN full-length enriched library, clone:A530029F09 product:unclassifiable, full insert sequence.AK020181 - Mus musculus adult male adrenal gland cDNA, RIKEN full-length enriched library, clone:7330410H16 product:unclassifiable, full insert sequence.AK047984 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130026L13 product:unclassifiable, full insert sequence.BC034413 - Mus musculus carbonic anhydrase 5b, mitochondrial, mRNA (cDNA clone MGC:35938 IMAGE:4221296), complete cds.AF192978 - Mus musculus carbonic anhydrase VB mRNA, complete cds; nuclear gene for mitochondrial product.AK085670 - Mus musculus 10 days lactation, adult female mammary gland cDNA, RIKEN full-length enriched library, clone:D730005F19 product:carbonic anhydrase 5b, mitochondrial, full insert sequence.AK046691 - Mus musculus 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430312O10 product:carbonic anhydrase 5b, mitochondrial, full insert sequence.
Biochemical and Signaling Pathways
KEGG - Kyoto Encyclopedia of Genes and Genomes mmu00910 - Nitrogen metabolism
Reactome (by CSHL, EBI, and GO) Protein Q9QZA0 (Reactome details) participates in the following event(s):R-MMU-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria)
R-MMU-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria)
R-MMU-1475029 Reversible hydration of carbon dioxide
R-MMU-1430728 Metabolism
Other Names for This Gene
Alternate Gene Symbols: Ca5b, CAH5B_MOUSE, NM_181315, Q8C3J9, Q8K014, Q9QZA0, uc009uvb.1, uc009uvb.2, uc009uvb.3UCSC ID: uc009uvb.3RefSeq Accession: NM_181315
Protein: Q9QZA0
(aka CAH5B_MOUSE or CA5B_MOUSE)
CCDS: CCDS30515.1
Gene Model Information
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.