Human Gene VWA3A (ENST00000563755.1) from GENCODE V44
  Description: Secreted (Potential). (from UniProt A6NCI4)
Gencode Transcript: ENST00000563755.1
Gencode Gene: ENSG00000175267.15
Transcript (Including UTRs)
   Position: hg38 chr16:22,146,272-22,155,902 Size: 9,631 Total Exon Count: 8 Strand: +
Coding Region
   Position: hg38 chr16:22,146,272-22,155,902 Size: 9,631 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:22,146,272-22,155,902)mRNA (may differ from genome)Protein (286 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblExonPrimerGencodeGeneCardsHGNCHPRD
LynxMGIneXtProtPubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: VWA3A_HUMAN
DESCRIPTION: RecName: Full=von Willebrand factor A domain-containing protein 3A; Flags: Precursor;
SUBCELLULAR LOCATION: Secreted (Potential).
SIMILARITY: Contains 2 VWFA domains.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 11.60 RPKM in Pituitary
Total median expression: 49.06 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002035 - VWF_A

ModBase Predicted Comparative 3D Structure on A6NCI4
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005576 extracellular region


-  Descriptions from all associated GenBank mRNAs
  LP896009 - Sequence 873 from Patent EP3253886.
AK128606 - Homo sapiens cDNA FLJ46765 fis, clone TRACH3024512.
BC109294 - Homo sapiens cDNA clone IMAGE:40034416.
BC109295 - Homo sapiens von Willebrand factor A domain containing 3A, mRNA (cDNA clone IMAGE:40034418), partial cds.
BC038400 - Homo sapiens von Willebrand factor A domain containing 3A, mRNA (cDNA clone IMAGE:5193948), partial cds.
AK093467 - Homo sapiens cDNA FLJ36148 fis, clone TESTI2025161.
AX748144 - Sequence 1669 from Patent EP1308459.
AY360464 - Homo sapiens hypothetical protein LOC146177-like protein mRNA, complete cds; alternatively spliced.
JD437543 - Sequence 418567 from Patent EP1572962.
JD328069 - Sequence 309093 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A4QMU8, A6NCI4, A6NNC0, AY360464, Q6UTX4, Q6ZQZ9, Q8IUY6, Q8N9W1, uc010bxe.1, uc010bxe.2, VWA3A_HUMAN
UCSC ID: ENST00000563755.1
RefSeq Accession: NM_173615
Protein: A6NCI4 (aka VWA3A_HUMAN)

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.