Human Gene RBMS3 (ENST00000456853.1) from GENCODE V44
Description: Homo sapiens RNA binding motif single stranded interacting protein 3 (RBMS3), transcript variant 4, mRNA. (from RefSeq NM_001177712) RefSeq Summary (NM_001177712): This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]. Gencode Transcript: ENST00000456853.1 Gencode Gene: ENSG00000144642.22 Transcript (Including UTRs) Position: hg38 chr3:29,281,616-29,991,239 Size: 709,624 Total Exon Count: 14 Strand: + Coding Region Position: hg38 chr3:29,281,682-29,991,213 Size: 709,532 Coding Exon Count: 14
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6XE24
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
