Human Gene ADK (ENST00000541550.6) from GENCODE V44
Description: adenosine kinase (from HGNC ADK) RefSeq Summary (NM_001123): This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]. Gencode Transcript: ENST00000541550.6 Gencode Gene: ENSG00000156110.15 Transcript (Including UTRs) Position: hg38 chr10:74,176,770-74,708,934 Size: 532,165 Total Exon Count: 12 Strand: + Coding Region Position: hg38 chr10:74,176,873-74,708,356 Size: 531,484 Coding Exon Count: 12
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
