Human Gene ZNF835 (uc010ygn.2)
  Description: Homo sapiens zinc finger protein 835 (ZNF835), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:57,174,020-57,183,123 Size: 9,104 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chr19:57,174,953-57,176,566 Size: 1,614 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr19:57,174,020-57,183,123)mRNA (may differ from genome)Protein (537 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Zinc finger protein 835;
FUNCTION: May be involved in transcriptional regulation.
SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family.
SIMILARITY: Contains 14 C2H2-type zinc fingers.
SEQUENCE CAUTION: Sequence=AAD23609.1; Type=Erroneous gene model prediction;

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.24 RPKM in Brain - Cerebellum
Total median expression: 50.15 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -79.90227-0.352 Picture PostScript Text
3' UTR -336.20933-0.360 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00096 - Zinc finger, C2H2 type

SCOP Domains:
48695 - Multiheme cytochromes
57667 - C2H2 and C2HC zinc fingers

ModBase Predicted Comparative 3D Structure on Q9Y2P0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter

Cellular Component:
GO:0005634 nucleus

-  Descriptions from all associated GenBank mRNAs
  LP896147 - Sequence 1011 from Patent EP3253886.
AK023017 - Homo sapiens cDNA FLJ12955 fis, clone NT2RP2005496, moderately similar to ZINC FINGER PROTEIN 135.
JD447448 - Sequence 428472 from Patent EP1572962.
JD120568 - Sequence 101592 from Patent EP1572962.
JD085760 - Sequence 66784 from Patent EP1572962.
JD311803 - Sequence 292827 from Patent EP1572962.
JD560468 - Sequence 541492 from Patent EP1572962.
JD503481 - Sequence 484505 from Patent EP1572962.
JD108133 - Sequence 89157 from Patent EP1572962.
JD242943 - Sequence 223967 from Patent EP1572962.
JD265538 - Sequence 246562 from Patent EP1572962.
JD254818 - Sequence 235842 from Patent EP1572962.
JD074139 - Sequence 55163 from Patent EP1572962.
JD065878 - Sequence 46902 from Patent EP1572962.
JD242951 - Sequence 223975 from Patent EP1572962.
JD242950 - Sequence 223974 from Patent EP1572962.
JD396188 - Sequence 377212 from Patent EP1572962.
JD519113 - Sequence 500137 from Patent EP1572962.
JD489196 - Sequence 470220 from Patent EP1572962.
JD409300 - Sequence 390324 from Patent EP1572962.
JD523044 - Sequence 504068 from Patent EP1572962.
JD306816 - Sequence 287840 from Patent EP1572962.
JD519097 - Sequence 500121 from Patent EP1572962.
JD212890 - Sequence 193914 from Patent EP1572962.
JD407502 - Sequence 388526 from Patent EP1572962.
JD152186 - Sequence 133210 from Patent EP1572962.
JD526239 - Sequence 507263 from Patent EP1572962.
JD352923 - Sequence 333947 from Patent EP1572962.
AK299565 - Homo sapiens cDNA FLJ54874 complete cds, moderately similar to Zinc finger protein 135.
JD513479 - Sequence 494503 from Patent EP1572962.
JD050597 - Sequence 31621 from Patent EP1572962.
JD097306 - Sequence 78330 from Patent EP1572962.
JD293829 - Sequence 274853 from Patent EP1572962.
JD076718 - Sequence 57742 from Patent EP1572962.
JD370327 - Sequence 351351 from Patent EP1572962.
JD265142 - Sequence 246166 from Patent EP1572962.
JD371477 - Sequence 352501 from Patent EP1572962.
JD210726 - Sequence 191750 from Patent EP1572962.
JD129355 - Sequence 110379 from Patent EP1572962.
JD458651 - Sequence 439675 from Patent EP1572962.
JD462139 - Sequence 443163 from Patent EP1572962.
JD336667 - Sequence 317691 from Patent EP1572962.
JD461218 - Sequence 442242 from Patent EP1572962.
JD382979 - Sequence 364003 from Patent EP1572962.
JD201092 - Sequence 182116 from Patent EP1572962.
JD382979 - Sequence 364003 from Patent EP1572962.
JD483953 - Sequence 464977 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B7Z5Y0, G3V1S0, NM_001005850, NP_001005850, Q9Y2P0, ZN835_HUMAN
UCSC ID: uc010ygn.2
RefSeq Accession: NM_001005850
Protein: Q9Y2P0 (aka ZN835_HUMAN)
CCDS: CCDS56105.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001005850.2
exon count: 2CDS single in 3' UTR: no RNA size: 2774
ORF size: 1614CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 3374.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.