ID:KLF15_HUMAN DESCRIPTION: RecName: Full=Krueppel-like factor 15; AltName: Full=Kidney-enriched krueppel-like factor; FUNCTION: Transcriptional activator. Binds to the GA element of the CLCNKA promoter. SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Highly expressed in liver, followed by heart, skeletal muscle, and kidney. Not expressed in bone marrow or lymphoid tissues. SIMILARITY: Belongs to the Sp1 C2H2-type zinc-finger protein family. SIMILARITY: Contains 3 C2H2-type zinc fingers.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9UIH9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0003676 nucleic acid binding GO:0003677 DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding GO:0005515 protein binding GO:0044212 transcription regulatory region DNA binding GO:0046872 metal ion binding
Biological Process: GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006366 transcription from RNA polymerase II promoter GO:0010001 glial cell differentiation GO:0010468 regulation of gene expression GO:0014898 cardiac muscle hypertrophy in response to stress GO:0045893 positive regulation of transcription, DNA-templated GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0046326 positive regulation of glucose import GO:0072112 glomerular visceral epithelial cell differentiation GO:2000757 negative regulation of peptidyl-lysine acetylation GO:2001275 positive regulation of glucose import in response to insulin stimulus
US Server
Sequence and Links to Tools and Databases 
Microarray Expression Data 
