Human Gene MUC19 (uc021qwv.1) Description and Page Index
  Description: SubName: Full=MUC19 variant 13; Flags: Fragment;
Transcript (Including UTRs)
   Position: hg19 chr12:40,787,196-40,813,035 Size: 25,840 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg19 chr12:40,787,250-40,813,034 Size: 25,785 Coding Exon Count: 7 

Page IndexSequence and LinksGenetic AssociationsMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:40,787,196-40,813,035)mRNA (may differ from genome)Protein (207 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaCGAP
EnsemblExonPrimerGeneCardsHGNCLynxMGI
PubMedStanford SOURCEUniProtKB

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): MUC19
CDC HuGE Published Literature: MUC19
Positive Disease Associations: Crohn's disease
Related Studies:
  1. Crohn's disease
    Barrett ,et al. 2008, Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease, Nature genetics 2008 40- 8 : 955-62. [PubMed 18587394]

-  MalaCards Disease Associations
  MalaCards Gene Search: MUC19
Diseases sorted by gene-association score: colorectal cancer 1 (2)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.69 RPKM in Minor Salivary Gland
Total median expression: 7.45 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -4.5054-0.083 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on G3CIH2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  HM801842 - Homo sapiens MUC19 variant 12 (MUC19) mRNA, complete cds, alternatively spliced.
HM801843 - Homo sapiens MUC19 variant 1 (MUC19) mRNA, partial cds, alternatively spliced.
HM801844 - Homo sapiens MUC19 variant 2 (MUC19) mRNA, partial cds, alternatively spliced.
HM801845 - Homo sapiens MUC19 variant 3 (MUC19) mRNA, partial cds, alternatively spliced.
HM801846 - Homo sapiens MUC19 variant 4 (MUC19) mRNA, partial cds, alternatively spliced.
HM801847 - Homo sapiens MUC19 variant 5 (MUC19) mRNA, partial cds, alternatively spliced.
HM801848 - Homo sapiens MUC19 variant 6 (MUC19) mRNA, partial cds, alternatively spliced.
HM801849 - Homo sapiens MUC19 variant 7 (MUC19) mRNA, partial cds, alternatively spliced.
HM801850 - Homo sapiens MUC19 variant 8 (MUC19) mRNA, partial cds, alternatively spliced.
HM801851 - Homo sapiens MUC19 variant 9 (MUC19) mRNA, partial cds, alternatively spliced.
HM801852 - Homo sapiens MUC19 variant 10 (MUC19) mRNA, partial cds, alternatively spliced.
HM801853 - Homo sapiens MUC19 variant 11 (MUC19) mRNA, partial cds, alternatively spliced.
HM801855 - Homo sapiens MUC19 variant 13 (MUC19) mRNA, partial cds, alternatively spliced.
HM801856 - Homo sapiens MUC19 variant 14 (MUC19) mRNA, partial cds, alternatively spliced.
HM801857 - Homo sapiens MUC19 variant 15-like (MUC19) mRNA, partial sequence, alternatively spliced.
HM801858 - Homo sapiens MUC19 variant 16-like (MUC19) mRNA, partial sequence, alternatively spliced.
HM801859 - Homo sapiens MUC19 variant 17 (MUC19) mRNA, partial cds, alternatively spliced.
HM801860 - Homo sapiens MUC19 variant 18 (MUC19) mRNA, partial cds, alternatively spliced.
HM801861 - Homo sapiens MUC19 variant 19 (MUC19) mRNA, partial cds, alternatively spliced.
HM801862 - Homo sapiens MUC19 variant 20 (MUC19) mRNA, partial cds, alternatively spliced.

-  Other Names for This Gene
  Alternate Gene Symbols: G3CIH2, G3CIH2_HUMAN, HM801855
UCSC ID: uc021qwv.1
Representative RNA: HM801855
Protein: G3CIH2

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: HM801855.1
exon count: 7CDS single in 3' UTR: no RNA size: 676
ORF size: 621CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1371.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.