Human Gene TMEM119 (uc021rdl.1) Description and Page Index
  Description: Homo sapiens transmembrane protein 119 (TMEM119), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr12:108,985,308-108,986,159 Size: 852 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg19 chr12:108,985,308-108,986,159 Size: 852 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesMicroarray Expression
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:108,985,308-108,986,159)mRNA (may differ from genome)Protein (283 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaCGAP
Entrez GeneExonPrimerGeneCardsHGNCHPRDLynx
MGIneXtProtPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: TM119_HUMAN
DESCRIPTION: RecName: Full=Transmembrane protein 119; Flags: Precursor;
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
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+  Microarray Expression Data
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-  Protein Domain and Structure Information
  Pfam Domains:
PF15724 - TMEM119 family

ModBase Predicted Comparative 3D Structure on Q4V9L6
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
 Protein SequenceProtein Sequence   
 AlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003674 molecular_function

Biological Process:
GO:0001503 ossification
GO:0001649 osteoblast differentiation
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0030501 positive regulation of bone mineralization
GO:0031214 biomineral tissue development
GO:0033690 positive regulation of osteoblast proliferation
GO:0045669 positive regulation of osteoblast differentiation
GO:0048515 spermatid differentiation
GO:1903012 positive regulation of bone development

Cellular Component:
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AK097290 - Homo sapiens cDNA FLJ39971 fis, clone SPLEN2028066.
AK075501 - Homo sapiens cDNA PSEC0199 fis, clone HEMBA1001680.
BC096825 - Homo sapiens transmembrane protein 119, mRNA (cDNA clone MGC:111384 IMAGE:30558500), complete cds.
AY358389 - Homo sapiens clone DNA58852 VSAA731 (UNQ731) mRNA, complete cds.
AK301202 - Homo sapiens cDNA FLJ54181 complete cds.
AK295288 - Homo sapiens cDNA FLJ55058 complete cds.
AB464311 - Synthetic construct DNA, clone: pF1KB7118, Homo sapiens TMEM119 gene for transmembrane protein 119, without stop codon, in Flexi system.

-  Other Names for This Gene
  Alternate Gene Symbols: CCDS9119, NM_181724, NP_859075, PSEC0199, Q4V9L6, Q6UXE5, Q8N2F5, TM119_HUMAN, UNQ731/PRO1415
UCSC ID: uc021rdl.1
Representative RNA: CCDS9119 Protein: Q4V9L6 (aka TM119_HUMAN)
CCDS: CCDS9119.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: CCDS9119.1
exon count: 1CDS single in 3' UTR: no RNA size: 852
ORF size: 852CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1895.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.