Human Gene SMIM17 (uc021vch.1)
  Description: Homo sapiens small integral membrane protein 17 (SMIM17), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:57,154,527-57,168,614 Size: 14,088 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr19:57,157,036-57,166,581 Size: 9,546 Coding Exon Count: 3 

Page IndexSequence and LinksGene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr19:57,154,527-57,168,614)mRNA (may differ from genome)Protein (118 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsH-INVHGNC

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.04 RPKM in Brain - Hypothalamus
Total median expression: 44.64 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -67.20152-0.442 Picture PostScript Text
3' UTR -479.242033-0.236 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on I3L0M8
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     

-  Descriptions from all associated GenBank mRNAs
  AK095199 - Homo sapiens cDNA FLJ37880 fis, clone BRSTN2000220.
JD405361 - Sequence 386385 from Patent EP1572962.
JD048371 - Sequence 29395 from Patent EP1572962.
JD068585 - Sequence 49609 from Patent EP1572962.
JD440131 - Sequence 421155 from Patent EP1572962.
JD255900 - Sequence 236924 from Patent EP1572962.
JD135125 - Sequence 116149 from Patent EP1572962.
JD338926 - Sequence 319950 from Patent EP1572962.
JD553986 - Sequence 535010 from Patent EP1572962.
JD566993 - Sequence 548017 from Patent EP1572962.
JD153089 - Sequence 134113 from Patent EP1572962.
JD140609 - Sequence 121633 from Patent EP1572962.
JD153091 - Sequence 134115 from Patent EP1572962.
JD198376 - Sequence 179400 from Patent EP1572962.
JD153090 - Sequence 134114 from Patent EP1572962.
JD198375 - Sequence 179399 from Patent EP1572962.
JD272025 - Sequence 253049 from Patent EP1572962.
JD527555 - Sequence 508579 from Patent EP1572962.
JD160945 - Sequence 141969 from Patent EP1572962.
JD546527 - Sequence 527551 from Patent EP1572962.
JD546528 - Sequence 527552 from Patent EP1572962.
JD492104 - Sequence 473128 from Patent EP1572962.
JD365500 - Sequence 346524 from Patent EP1572962.
JD365501 - Sequence 346525 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: hCG_1647586, I3L0M8, I3L0M8_HUMAN, NM_001193628, NP_001180557
UCSC ID: uc021vch.1
RefSeq Accession: NM_001193628
Protein: I3L0M8 CCDS: CCDS58683.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001193628.1
exon count: 4CDS single in 3' UTR: no RNA size: 2542
ORF size: 357CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 914.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: yes # AT/AC introns 0
selenocysteine: no end bleed into intron: 1792# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.