Human Gene ZC4H2 (uc022byc.1) Description and Page Index
Description: Homo sapiens zinc finger, C4H2 domain containing (ZC4H2), transcript variant 5, non-coding RNA. RefSeq Summary (NM_001243804): This gene encodes a member of the zinc finger domain-containing protein family. This family member has a C-terminal zinc finger domain that is characterized by four cysteine residues and two histidine residues, and it also includes a coiled-coil region. This protein has been detected as an autoantigen in hepatocellular carcinoma patients. This gene has been identified as a potential candidate for X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]. Transcript (Including UTRs) Position: hg19 chrX:64,135,682-64,196,413 Size: 60,732 Total Exon Count: 5 Strand: - Coding Region Position: hg19 chrX:64,137,663-64,141,852 Size: 4,190 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF10146 - Zinc finger-containing protein
ModBase Predicted Comparative 3D Structure on Q9NQZ6
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary