Human Gene MIR5189 (uc031qxh.1) Description and Page Index
  Description: Homo sapiens microRNA 5189 (MIR5189), microRNA.
RefSeq Summary (NR_049821): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. ##Evidence-Data-START## Transcript is intronless :: LM611540.1 [ECO:0000345] ##Evidence-Data-END##
Transcript (Including UTRs)
   Position: hg19 chr16:88,535,326-88,535,439 Size: 114 Total Exon Count: 1 Strand: +

Page IndexSequence and LinksRNA-Seq ExpressionMicroarray ExpressionOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr16:88,535,326-88,535,439)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerHGNCLynxPubMedStanford SOURCE

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.00 RPKM in Adipose - Subcutaneous
Total median expression: 0.00 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Descriptions from all associated GenBank mRNAs
  LF208344 - JP 2014500723-A/15847: Polycomb-Associated Non-Coding RNAs.
HZ409639 - JP 2015528002-A/2236: CHIRAL CONTROL.
LG052973 - KR 1020150036642-A/2239: CHIRAL CONTROL.
HW906956 - WO 2015037656-A/171: Autophagy-regulating microRNA.
HZ083254 - JP 2015513906-A/611: Stem Cell Microparticles.
HZ437035 - JP 2015529450-A/611: Stem Cell Microparticles.
HZ482128 - JP 2015535430-A/2634: TERMINALLY MODIFIED RNA.
JC172239 - Sequence 611 from Patent WO2013150303.
JC514791 - Sequence 5044 from Patent WO2014113089.
JC573050 - Sequence 611 from Patent WO2014125276.
JC582738 - Sequence 611 from Patent WO2014125277.
JE954434 - Sequence 611 from Patent WO2015052526.
JE956187 - Sequence 611 from Patent WO2015052527.
LF137939 - JP 2016507550-A/611: Method of Producing Microparticles.
LF160884 - JP 2016513950-A/950: Oligomers with improved off-target profile.
LF162904 - JP 2016513095-A/611: Stem Cell Microparticles and miRNA.
LF953656 - JP 2016534103-A/611: Stem Cell Microparticles and miRNA.
LG006001 - KR 1020150004822-A/611: STEM CELL MICROPARTICLES.
LG053697 - KR 1020150059168-A/611: STEM CELL MICROPARTICLES.
LG240936 - KR 1020160035087-A/611: STEM CELL MICROPARTICLES AND MIRNA.
LQ072379 - Sequence 2703 from Patent EP2964234.
LV471021 - JP 2016534036-A/611: Stem Cell Microparticles and miRNA.
HW906957 - WO 2015037656-A/172: Autophagy-regulating microRNA.
MA733764 - JP 2017140048-A/2634: TERMINALLY MODIFIED RNA.
MA405884 - WO 2018155427-A/658: A probe with reduced false positive binding, a method to desing the probe, and the use thereof.
MA443921 - JP 2018138019-A/15847: Polycomb-Associated Non-Coding RNAs.
MP129711 - Sequence 611 from Patent EP3470073.
MP162634 - Sequence 611 from Patent WO2019069093.
MB407065 - WO 2019159884-A/555: Kit, device, and method for detection of dementia.
MB406667 - WO 2019159884-A/157: Kit, device, and method for detection of dementia.
MB407477 - WO 2019159884-A/967: Kit, device, and method for detection of dementia.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_049821
UCSC ID: uc031qxh.1
RefSeq Accession: NR_049821

-  Gene Model Information
category: noncoding nonsense-mediated-decay: no RNA accession: NR_049821.1
exon count: 1CDS single in 3' UTR: no RNA size: 114
ORF size: 0CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 248.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.