Human Gene LSP1 (ENST00000457279.5) from GENCODE V44
Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt E7EMG9) RefSeq Summary (NM_001013255): This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000457279.5 Gencode Gene: ENSG00000130592.17 Transcript (Including UTRs) Position: hg38 chr11:1,869,642-1,886,866 Size: 17,225 Total Exon Count: 8 Strand: + Coding Region Position: hg38 chr11:1,869,704-1,886,866 Size: 17,163 Coding Exon Count: 8
ID:E7EMG9_HUMAN DESCRIPTION: SubName: Full=Lymphocyte-specific protein 1; Flags: Fragment; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on E7EMG9
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
LF207981 - JP 2014500723-A/15484: Polycomb-Associated Non-Coding RNAs. MA443558 - JP 2018138019-A/15484: Polycomb-Associated Non-Coding RNAs. AK222733 - Homo sapiens mRNA for lymphocyte-specific protein 1 variant, clone: DMC01679. M33552 - Human lymphocyte-specific protein 1 (LSP1) mRNA, complete cds. BC001785 - Homo sapiens lymphocyte-specific protein 1, mRNA (cDNA clone MGC:2290 IMAGE:3542307), complete cds. X55188 - H.sapiens mRNA WP34 for phosphorylated lymphocyte differentiation and activation antigen. AK290279 - Homo sapiens cDNA FLJ76079 complete cds, highly similar to Homo sapiens lymphocyte-specific protein 1 (LSP1), mRNA. S67783 - lymphocyte-specific protein 1=47 kda actin binding protein [human, HL60, mRNA, 1039 nt]. CU674886 - Synthetic construct Homo sapiens gateway clone IMAGE:100017046 5' read LSP1 mRNA. CR541754 - Homo sapiens full open reading frame cDNA clone RZPDo834H1029D for gene LSP1, lymphocyte-specific protein 1; complete cds, without stopcodon. KJ897144 - Synthetic construct Homo sapiens clone ccsbBroadEn_06538 LSP1 gene, encodes complete protein. CR541728 - Homo sapiens full open reading frame cDNA clone RZPDo834D1029D for gene LSP1, lymphocyte-specific protein 1; complete cds, incl. stopcodon. AK092071 - Homo sapiens cDNA FLJ34752 fis, clone NESOP2000452, highly similar to Lymphocyte-specific protein 1. AX747343 - Sequence 868 from Patent EP1308459. AK056576 - Homo sapiens cDNA FLJ32014 fis, clone NTONG1000047, highly similar to Lymphocyte-specific protein 1. AK292033 - Homo sapiens cDNA FLJ77847 complete cds. HZ459683 - WO 2015182781-A/386: Kit or device and method for detecting pancreatic cancer. HZ460242 - WO 2015190542-A/248: Kit or device and method for detecting biliary tract cancer. HZ460748 - WO 2015190584-A/245: Kit or device and method for detecting prostate cancer. HZ461456 - WO 2015190586-A/269: Kit and method for detecting colon cancer. HZ462263 - WO 2015190591-A/418: Kit and method for detecting breast cancer. HZ463184 - WO 2015194535-A/278: Kit and method for detecting stomach cancer. HZ463840 - WO 2015194610-A/276: Kit and method for detecting lung cancer. HZ464556 - WO 2015194615-A/374: Kit or device and method for detecting hepatic cancer. HZ465227 - WO 2015194627-A/280: Kit and method for detecting esophageal cancer. LY481123 - KR 1020170010856-A/386: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD. LY495869 - KR 1020170015509-A/248: DETECTION KIT OR DEVICE AND DETECTION METHOD FOR BILIARY TRACT CANCER. LY496410 - KR 1020170018406-A/280: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY497099 - KR 1020170016485-A/269: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY497741 - KR 1020170018409-A/276: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD. LY498457 - KR 1020170018411-A/374: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY499266 - KR 1020170018412-A/418: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER. LY499997 - KR 1020170019425-A/278: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY500621 - KR 1020170016490-A/245: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LZ238702 - WO 2017171048-A/363: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas. MS869034 - Sequence 248 from Patent EP3156500. MS869540 - Sequence 245 from Patent EP3156483. MS880581 - Sequence 418 from Patent EP3156498. MS884286 - Sequence 269 from Patent EP3156499. MS885116 - Sequence 278 from Patent EP3156503. MS994418 - Sequence 280 from Patent EP3159406. MS996807 - Sequence 276 from Patent EP3159416. HZ459648 - WO 2015182781-A/351: Kit or device and method for detecting pancreatic cancer. HZ460091 - WO 2015190542-A/97: Kit or device and method for detecting biliary tract cancer. HZ460562 - WO 2015190584-A/59: Kit or device and method for detecting prostate cancer. HZ461262 - WO 2015190586-A/75: Kit and method for detecting colon cancer. HZ461985 - WO 2015190591-A/140: Kit and method for detecting breast cancer. HZ462985 - WO 2015194535-A/79: Kit and method for detecting stomach cancer. HZ463665 - WO 2015194610-A/101: Kit and method for detecting lung cancer. HZ464338 - WO 2015194615-A/156: Kit or device and method for detecting hepatic cancer. HZ465012 - WO 2015194627-A/65: Kit and method for detecting esophageal cancer. LP951755 - Sequence 261 from Patent WO2017157650. LQ724809 - Sequence 442 from Patent WO2018096084. LY481088 - KR 1020170010856-A/351: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD. LY495718 - KR 1020170015509-A/97: DETECTION KIT OR DEVICE AND DETECTION METHOD FOR BILIARY TRACT CANCER. LY496195 - KR 1020170018406-A/65: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY496905 - KR 1020170016485-A/75: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY497566 - KR 1020170018409-A/101: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD. LY498239 - KR 1020170018411-A/156: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY498988 - KR 1020170018412-A/140: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER. LY499798 - KR 1020170019425-A/79: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY500435 - KR 1020170016490-A/59: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LZ238446 - WO 2017171048-A/107: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas. MS868883 - Sequence 97 from Patent EP3156500. MS869354 - Sequence 59 from Patent EP3156483. MS880303 - Sequence 140 from Patent EP3156498. MS884092 - Sequence 75 from Patent EP3156499. MS884917 - Sequence 79 from Patent EP3156503. MS994203 - Sequence 65 from Patent EP3159406. MS996632 - Sequence 101 from Patent EP3159416. AK093859 - Homo sapiens cDNA FLJ36540 fis, clone TRACH2005710, highly similar to LYMPHOCYTE-SPECIFIC PROTEIN LSP1. LF370690 - JP 2014500723-A/178193: Polycomb-Associated Non-Coding RNAs. MA606267 - JP 2018138019-A/178193: Polycomb-Associated Non-Coding RNAs. LF370691 - JP 2014500723-A/178194: Polycomb-Associated Non-Coding RNAs. MA606268 - JP 2018138019-A/178194: Polycomb-Associated Non-Coding RNAs. MA806182 - WO 2018199275-A/442: Kit, device and method for detection of ovary tumor. MA805905 - WO 2018199275-A/165: Kit, device and method for detection of ovary tumor. MA822820 - WO 2019004436-A/633: Kit, device, and method for detection of lung cancer. MA822485 - WO 2019004436-A/298: Kit, device, and method for detection of lung cancer. LY616466 - KR 1020180129785-A/363: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR. LY616210 - KR 1020180129785-A/107: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.