Human Gene ALDOC (ENST00000395319.7) from GENCODE V44
Description: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. (from UniProt A8MVZ9) RefSeq Summary (NM_005165): This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000395319.7 Gencode Gene: ENSG00000109107.14 Transcript (Including UTRs) Position: hg38 chr17:28,573,115-28,576,885 Size: 3,771 Total Exon Count: 8 Strand: - Coding Region Position: hg38 chr17:28,573,526-28,575,532 Size: 2,007 Coding Exon Count: 7
ID:A8MVZ9_HUMAN DESCRIPTION: RecName: Full=Fructose-bisphosphate aldolase; EC=4.1.2.13; CATALYTIC ACTIVITY: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3- phosphate and glycerone phosphate from D-glucose: step 4/4. SIMILARITY: Belongs to the class I fructose-bisphosphate aldolase family. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on A8MVZ9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
