Human Gene FLOT2 (ENST00000585169.6) from GENCODE V44
Description: Homo sapiens flotillin 2 (FLOT2), transcript variant 2, mRNA. (from RefSeq NM_001330170) RefSeq Summary (NM_001330170): Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENST00000585169.6 Gencode Gene: ENSG00000132589.16 Transcript (Including UTRs) Position: hg38 chr17:28,879,339-28,897,733 Size: 18,395 Total Exon Count: 11 Strand: - Coding Region Position: hg38 chr17:28,880,561-28,897,574 Size: 17,014 Coding Exon Count: 11
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF01145 - SPFH domain / Band 7 family
ModBase Predicted Comparative 3D Structure on J3QLD9
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.