Human Gene UFD1 (ENST00000474226.1) from GENCODE V44
Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt C9J7C8) RefSeq Summary (NM_001035247): The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]. Gencode Transcript: ENST00000474226.1 Gencode Gene: ENSG00000070010.19 Transcript (Including UTRs) Position: hg38 chr22:19,467,895-19,479,144 Size: 11,250 Total Exon Count: 3 Strand: - Coding Region Position: hg38 chr22:19,467,895-19,471,785 Size: 3,891 Coding Exon Count: 2
ID:C9J7C8_HUMAN DESCRIPTION: SubName: Full=Ubiquitin fusion degradation protein 1 homolog; Flags: Fragment; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF03152 - Ubiquitin fusion degradation protein UFD1
ModBase Predicted Comparative 3D Structure on C9J7C8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
