Human Gene PRKCD (ENST00000487897.5) from GENCODE V44
Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt C9J9P1) RefSeq Summary (NM_001316327): The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome. [provided by RefSeq, Aug 2017]. Gencode Transcript: ENST00000487897.5 Gencode Gene: ENSG00000163932.16 Transcript (Including UTRs) Position: hg38 chr3:53,161,521-53,181,267 Size: 19,747 Total Exon Count: 5 Strand: + Coding Region Position: hg38 chr3:53,178,423-53,181,267 Size: 2,845 Coding Exon Count: 3
ID:C9J9P1_HUMAN DESCRIPTION: SubName: Full=Protein kinase C delta type; Flags: Fragment; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on C9J9P1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.