Human Gene FBP1 (ENST00000414122.1) from GENCODE V44
Description: Belongs to the FBPase class 1 family. (from UniProt Q5VZC3) RefSeq Summary (NM_001127628): Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Gencode Transcript: ENST00000414122.1 Gencode Gene: ENSG00000165140.12 Transcript (Including UTRs) Position: hg38 chr9:94,606,815-94,640,137 Size: 33,323 Total Exon Count: 5 Strand: - Coding Region Position: hg38 chr9:94,606,815-94,620,409 Size: 13,595 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q5VZC3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.