Human Gene TP53TG3 (uc010cay.1)
  Description: TP53 target 3
Transcript (Including UTRs)
   Position: hg18 chr16:33,111,657-33,115,688 Size: 4,032 Total Exon Count: 2 Strand: +
Coding Region
   Position: hg18 chr16:33,113,116-33,114,661 Size: 1,546 Coding Exon Count: 2 

Page IndexSequence and LinksPrimersCTDMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2009-03-03

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:33,111,657-33,115,688)mRNA (may differ from genome)Protein (124 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCMGIOMIMPubMedTreefam
UniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
Ratios
      
      
      
     
    
     
Absolute
      
       
      
      
     
    
Ratios
      
       
      
      
     
    
Absolute
   
     
     
Ratios
   
     
     
Absolute

Affymetrix All Exon Microarrays

           
Ratios

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -455.471459-0.312 Picture PostScript Text
3' UTR -222.881027-0.217 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q9ULZ0-2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AL133588 - Homo sapiens mRNA; cDNA DKFZp434I199 (from clone DKFZp434I199).
AB023508 - Homo sapiens mRNA for TP53TG3b, complete cds.
BC096733 - Homo sapiens TP53 target 3, mRNA (cDNA clone MGC:119889 IMAGE:40015196), complete cds.
BC098165 - Homo sapiens TP53 target 3, mRNA (cDNA clone MGC:119888 IMAGE:40015195), complete cds.
AK312220 - Homo sapiens cDNA, FLJ92509, Homo sapiens TP53TG3 protein (TP53TG3), mRNA.
CR541650 - Homo sapiens full open reading frame cDNA clone RZPDo834D0627D for gene TP53TG3, TP53TG3 protein; complete cds, without stopcodon.
AK097435 - Homo sapiens cDNA FLJ40116 fis, clone TESTI2009239.
JD358945 - Sequence 339969 from Patent EP1572962.
JD565979 - Sequence 547003 from Patent EP1572962.
JD509272 - Sequence 490296 from Patent EP1572962.
JD553103 - Sequence 534127 from Patent EP1572962.
JD313827 - Sequence 294851 from Patent EP1572962.
JD311343 - Sequence 292367 from Patent EP1572962.
JD046516 - Sequence 27540 from Patent EP1572962.
JD273951 - Sequence 254975 from Patent EP1572962.
JD300152 - Sequence 281176 from Patent EP1572962.
JD296521 - Sequence 277545 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_016212, NP_057296, Q9ULZ0-2, TP53TG3A, TP53TG3B, TP53TG3C, TP53TG3D, uc002edo.1
UCSC ID: uc010cay.1
RefSeq Accession: NM_001099687
Protein: Q9ULZ0-2, splice isoform of Q9ULZ0

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_016212.2
exon count: 2CDS single in 3' UTR: no RNA size: 2034
ORF size: 375CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: -79.00frame shift in genome: no % Coverage: 99.75
has start codon: yes stop codon in genome: no # of Alignments: 3
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.