Description: ADP-ribosylation factor related protein 1 RefSeq Summary (NM_001134758): The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012]. Transcript (Including UTRs) Position: hg18 chr20:61,801,253-61,809,809 Size: 8,557 Total Exon Count: 8 Strand: - Coding Region Position: hg18 chr20:61,802,239-61,808,887 Size: 6,649 Coding Exon Count: 7
ID:ARFRP_HUMAN DESCRIPTION: RecName: Full=ADP-ribosylation factor-related protein 1; Short=ARF-related protein 1; Short=ARP; FUNCTION: Possibly involved in plasma membrane-related signaling events. SUBUNIT: Interacts with SYS1. SUBCELLULAR LOCATION: Golgi apparatus. TISSUE SPECIFICITY: Found in most tissues. SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q13795
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007165 signal transduction GO:0007369 gastrulation GO:0034067 protein localization to Golgi apparatus GO:0042147 retrograde transport, endosome to Golgi GO:0043001 Golgi to plasma membrane protein transport