Human Gene C7orf45 (uc003vpp.1)
  Description: hypothetical protein LOC136263
Transcript (Including UTRs)
   Position: hg18 chr7:129,634,954-129,644,733 Size: 9,780 Total Exon Count: 3 Strand: +
Coding Region
   Position: hg18 chr7:129,634,987-129,643,546 Size: 8,560 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsPrimersMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2009-03-03

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:129,634,954-129,644,733)mRNA (may differ from genome)Protein (244 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkH-INV
HPRDMGIPubMedTreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: CG045_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C7orf45;
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from U133A and GNF1H Chips

      
      
      
     
    
     
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Affymetrix All Exon Microarrays

           
Ratios

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -1.9033-0.058 Picture PostScript Text
3' UTR -371.601187-0.313 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q8WWF3
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  BC017587 - Homo sapiens chromosome 7 open reading frame 45, mRNA (cDNA clone MGC:26614 IMAGE:4838989), complete cds.
AK097635 - Homo sapiens cDNA FLJ40316 fis, clone TESTI2030342.
HQ447418 - Synthetic construct Homo sapiens clone IMAGE:100070741; CCSB001617_02 chromosome 7 open reading frame 45 (C7orf45) gene, encodes complete protein.
JD378347 - Sequence 359371 from Patent EP1572962.
JD350629 - Sequence 331653 from Patent EP1572962.
JD478591 - Sequence 459615 from Patent EP1572962.
JD558327 - Sequence 539351 from Patent EP1572962.
JD534811 - Sequence 515835 from Patent EP1572962.
JD534810 - Sequence 515834 from Patent EP1572962.
JD534809 - Sequence 515833 from Patent EP1572962.
JD366435 - Sequence 347459 from Patent EP1572962.
JD366436 - Sequence 347460 from Patent EP1572962.
JD517584 - Sequence 498608 from Patent EP1572962.
JD504363 - Sequence 485387 from Patent EP1572962.
JD492571 - Sequence 473595 from Patent EP1572962.
JD552751 - Sequence 533775 from Patent EP1572962.
JD543277 - Sequence 524301 from Patent EP1572962.
JD463837 - Sequence 444861 from Patent EP1572962.
JD564403 - Sequence 545427 from Patent EP1572962.
KJ895511 - Synthetic construct Homo sapiens clone ccsbBroadEn_04905 C7orf45 gene, encodes complete protein.
JD287561 - Sequence 268585 from Patent EP1572962.
JD049517 - Sequence 30541 from Patent EP1572962.
JD279372 - Sequence 260396 from Patent EP1572962.
JD233128 - Sequence 214152 from Patent EP1572962.
JD264300 - Sequence 245324 from Patent EP1572962.
JD178002 - Sequence 159026 from Patent EP1572962.
JD244884 - Sequence 225908 from Patent EP1572962.
JD318006 - Sequence 299030 from Patent EP1572962.
JD075303 - Sequence 56327 from Patent EP1572962.
JD052211 - Sequence 33235 from Patent EP1572962.
JD302507 - Sequence 283531 from Patent EP1572962.
JD148326 - Sequence 129350 from Patent EP1572962.
JD249883 - Sequence 230907 from Patent EP1572962.
JD238519 - Sequence 219543 from Patent EP1572962.
JD105739 - Sequence 86763 from Patent EP1572962.
JD159103 - Sequence 140127 from Patent EP1572962.
JD209029 - Sequence 190053 from Patent EP1572962.
JD274664 - Sequence 255688 from Patent EP1572962.
JD052709 - Sequence 33733 from Patent EP1572962.
JD325398 - Sequence 306422 from Patent EP1572962.
JD059728 - Sequence 40752 from Patent EP1572962.
JD059727 - Sequence 40751 from Patent EP1572962.
JD155868 - Sequence 136892 from Patent EP1572962.
JD155867 - Sequence 136891 from Patent EP1572962.
JD199907 - Sequence 180931 from Patent EP1572962.
JD155866 - Sequence 136890 from Patent EP1572962.
JD092093 - Sequence 73117 from Patent EP1572962.
JD292570 - Sequence 273594 from Patent EP1572962.
JD117236 - Sequence 98260 from Patent EP1572962.
JD117237 - Sequence 98261 from Patent EP1572962.
JD105897 - Sequence 86921 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: CG045_HUMAN, NM_145268, NP_660311, Q8WWF3
UCSC ID: uc003vpp.1
RefSeq Accession: NM_145268
Protein: Q8WWF3 (aka CG045_HUMAN)
CCDS: CCDS5816.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_145268.2
exon count: 3CDS single in 3' UTR: no RNA size: 1953
ORF size: 735CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1641.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.