Human Gene RPP30 (uc001khd.2)
Description: Homo sapiens ribonuclease P/MRP 30kDa subunit (RPP30), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr10:92,631,474-92,668,312 Size: 36,839 Total Exon Count: 14 Strand: +
Coding Region
Position: hg19 chr10:92,631,744-92,663,019 Size: 31,276 Coding Exon Count: 13
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): RPP30
CDC HuGE Published Literature: RPP30
Positive Disease Associations: Glucose
Related Studies: Glucose , , .
[PubMed 0 ]
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR016195 - Pol/histidinol_Pase-like
IPR002738 - RNase_P_p30
Pfam Domains: PF01876 - RNase P subunit p30
SCOP Domains: 89550 - PHP domain-like
ModBase Predicted Comparative 3D Structure on E9PB02
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
AK095810 - Homo sapiens cDNA FLJ38491 fis, clone FEBRA2023990.BC006991 - Homo sapiens ribonuclease P/MRP 30kDa subunit, mRNA (cDNA clone MGC:12256 IMAGE:3827681), complete cds.JD530745 - Sequence 511769 from Patent EP1572962.JD508960 - Sequence 489984 from Patent EP1572962.JD559849 - Sequence 540873 from Patent EP1572962.AL833628 - Homo sapiens mRNA; cDNA DKFZp686C1579 (from clone DKFZp686C1579).AK296196 - Homo sapiens cDNA FLJ57382 complete cds, highly similar to Ribonuclease P protein subunit p30 (EC 3.1.26.5).U77665 - Human RNaseP protein p30 (RPP30) mRNA, complete cds.AK312900 - Homo sapiens cDNA, FLJ93346, Homo sapiens ribonuclease P (30kD) (RPP30), mRNA.AK225532 - Homo sapiens mRNA for ribonuclease P variant, clone: KAT10347.KJ893074 - Synthetic construct Homo sapiens clone ccsbBroadEn_02468 RPP30 gene, encodes complete protein.DQ893181 - Synthetic construct clone IMAGE:100005811; FLH194795.01X; RZPDo839F0280D ribonuclease P/MRP 30kDa subunit (RPP30) gene, encodes complete protein.DQ896488 - Synthetic construct Homo sapiens clone IMAGE:100010948; FLH194791.01L; RZPDo839F0270D ribonuclease P/MRP 30kDa subunit (RPP30) gene, encodes complete protein.JD380447 - Sequence 361471 from Patent EP1572962.BC044601 - Homo sapiens cDNA clone IMAGE:4815080.JD501618 - Sequence 482642 from Patent EP1572962.JD091458 - Sequence 72482 from Patent EP1572962.JD150744 - Sequence 131768 from Patent EP1572962.JD240377 - Sequence 221401 from Patent EP1572962.JD339555 - Sequence 320579 from Patent EP1572962.JD351163 - Sequence 332187 from Patent EP1572962.JD544764 - Sequence 525788 from Patent EP1572962.JD044567 - Sequence 25591 from Patent EP1572962.JD304436 - Sequence 285460 from Patent EP1572962.JD110087 - Sequence 91111 from Patent EP1572962.JD065652 - Sequence 46676 from Patent EP1572962.JD203887 - Sequence 184911 from Patent EP1572962.JD471119 - Sequence 452143 from Patent EP1572962.JD160546 - Sequence 141570 from Patent EP1572962.JD108451 - Sequence 89475 from Patent EP1572962.JD309414 - Sequence 290438 from Patent EP1572962.JD473794 - Sequence 454818 from Patent EP1572962.JD066848 - Sequence 47872 from Patent EP1572962.JD271044 - Sequence 252068 from Patent EP1572962.JD252427 - Sequence 233451 from Patent EP1572962.JD166483 - Sequence 147507 from Patent EP1572962.JD274384 - Sequence 255408 from Patent EP1572962.JD252925 - Sequence 233949 from Patent EP1572962.JD303012 - Sequence 284036 from Patent EP1572962.JD297289 - Sequence 278313 from Patent EP1572962.JD308324 - Sequence 289348 from Patent EP1572962.JD438044 - Sequence 419068 from Patent EP1572962.JD142755 - Sequence 123779 from Patent EP1572962.JD561751 - Sequence 542775 from Patent EP1572962.JD552153 - Sequence 533177 from Patent EP1572962.JD133261 - Sequence 114285 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: E9PB02, E9PB02_HUMAN, NM_001104546, NP_001098016UCSC ID: uc001khd.2RefSeq Accession: NM_001104546
Protein: E9PB02
CCDS: CCDS44458.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001104546.1
exon count:
14 CDS single in 3' UTR:
no
RNA size:
4272
ORF size:
969 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1954.50 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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