Human Gene MARK2 (ENST00000502399.7) from GENCODE V44
Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt E9PC69) RefSeq Summary (NM_001039469): This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]. Gencode Transcript: ENST00000502399.7 Gencode Gene: ENSG00000072518.23 Transcript (Including UTRs) Position: hg38 chr11:63,839,295-63,909,573 Size: 70,279 Total Exon Count: 18 Strand: + Coding Region Position: hg38 chr11:63,839,507-63,909,237 Size: 69,731 Coding Exon Count: 18
ID:E9PC69_HUMAN DESCRIPTION: SubName: Full=Serine/threonine-protein kinase MARK2; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on E9PC69
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
