ID:NUP93_MOUSE DESCRIPTION: RecName: Full=Nuclear pore complex protein Nup93; AltName: Full=93 kDa nucleoporin; AltName: Full=CBP-interacting protein 4; AltName: Full=Nucleoporin Nup93; FUNCTION: Part of the nucleoporin complex; required for correct nuclear pore assembly (By similarity). SUBUNIT: Component of the p62 complex, a complex composed of NUP62 and NUP54. Forms a complex with NUP53, NUP155, NUP205 and lamin B; the interaction with NUP53 is direct (By similarity). SUBCELLULAR LOCATION: Nucleus, nuclear pore complex (By similarity). Nucleus membrane; Peripheral membrane protein (By similarity). Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore (By similarity). SIMILARITY: Belongs to the nucleoporin interacting component (NIC) family. SEQUENCE CAUTION: Sequence=BAC97865.2; Type=Frameshift; Positions=418, 784;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8BJ71
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0017056 structural constituent of nuclear pore
Biological Process: GO:0006998 nuclear envelope organization GO:0015031 protein transport GO:0016973 poly(A)+ mRNA export from nucleus GO:0051028 mRNA transport GO:0051292 nuclear pore complex assembly GO:0060391 positive regulation of SMAD protein import into nucleus GO:0060395 SMAD protein signal transduction GO:0072001 renal system development GO:0072015 glomerular visceral epithelial cell development GO:0090521 glomerular visceral epithelial cell migration GO:1903206 negative regulation of hydrogen peroxide-induced cell death
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