S. cerevisiae Gene AGE2 (YIL044C) Description and Page Index
  Description: ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector
Transcript (Including UTRs)
   Position: sacCer1 chr9:272,949-273,845 Size: 897 Total Exon Count: 1 Strand: -
Coding Region
   Position: sacCer1 chr9:272,949-273,845 Size: 897 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsMicroarray ExpressionProtein StructureOther Species
GO AnnotationsLocalizationOther NamesMethods
Data last updated: 2003-12-31

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr9:272,949-273,845)mRNAProtein (299 aa)
Gene SorterGenome BrowserOther Species FASTASGDUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=ADP-ribosylation factor GTPase-activating protein effector protein 2; Short=ARF GAP effector protein 2;
FUNCTION: GTPase-activating protein for the ADP ribosylation factor family (Potential).
SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus. Note=Associates with the Golgi complex.
MISCELLANEOUS: Present with 5350 molecules/cell in log phase SD medium.
SIMILARITY: Contains 1 Arf-GAP domain.

-  Microarray Expression Data
Expression ratio colors:

Genome-wide transcriptional analysis of the mitotic cell cycle, Cho et al.


-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001164 - ArfGAP

Pfam Domains:
PF01412 - Putative GTPase activating protein for Arf

ModBase Predicted Comparative 3D Structure on P40529
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanMouseRatZebrafishD. melanogaster
Genome BrowserGenome BrowserNo orthologNo orthologGenome Browser
Gene DetailsGene DetailsGene Details Gene Details
Gene SorterGene SorterGene Sorter Gene Sorter
Protein SequenceProtein Sequence  Protein Sequence
AlignmentAlignment  Alignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005096 GTPase activator activity
GO:0046872 metal ion binding

Biological Process:
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0043547 positive regulation of GTPase activity

Cellular Component:
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus

-  Protein Localization and Abundance
  SGD Localization: Golgi to vacuole
SGD Abundance: 5350 (range from 41 to 1590000)
Protein localization data from Huh et al. (2003), Nature 425:686-691
Protein abundance data from Ghaemmaghami et al. (2003) Nature 425:737-741
For more information see http://yeastgfp.yeastgenome.org.

-  Other Names for This Gene
Protein: P40529 (aka AGE2_YEAST or YIE4_YEAST)

-  SGD Genes Methods, Credits, and Data Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.