- Home
- Genomes
- Genome Browser
- Tools
- Mirrors
- Downloads
- My Data
- Projects
- Help
- About Us
ICAM-1 — NF-kappaB: " Inhibition of mTOR by this approach promoted whereas over-expression of mTOR inhibited thrombin induced transcriptional activity of NF-kappaB , an essential regulator of ICAM-1 transcription "
IkappaB kinase ⊣ mTOR: " Analysis of the NF-kappaB signaling pathway revealed that inhibition of mTOR potentiated IkappaB kinase activation resulting in a rapid and persistent phosphorylation of IkappaBalpha on Ser32 and Ser36, a requirement for IkappaBalpha degradation "
IkappaBalpha ⊣ mTOR: " Analysis of the NF-kappaB signaling pathway revealed that inhibition of mTOR potentiated IkappaB kinase activation resulting in a rapid and persistent phosphorylation of IkappaBalpha on Ser32 and Ser36, a requirement for IkappaBalpha degradation "
RelA/p65 ⊣ mTOR: " Consistent with these data, we observed a more efficient and stable nuclear localization of RelA/p65 and, subsequently, the DNA binding activity of NF-kappaB by thrombin following mTOR inhibition "
RelA/p65 ⊣ mTOR: " Consistent with these data, we observed a more efficient and stable nuclear localization of RelA/p65 and, subsequently, the DNA binding activity of NF-kappaB by thrombin following mTOR inhibition "
ICAM-1 ⊣ mTOR: " These data define a novel role of mTOR in down regulating thrombin induced ICAM-1 expression in endothelial cells by controlling a delayed and transient activation of NF-kappaB "