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MDC → lipopolysaccharide (LPS): " Ketotifen ( 5-50 microM ) significantly down-regulated lipopolysaccharide (LPS) induced MDC , MIG and IP-10 ( p < 0.05, each comparison ) in THP-1 cells and human primary monocytes in a dose dependent manner "
MIG → lipopolysaccharide (LPS): " Ketotifen ( 5-50 microM ) significantly down-regulated lipopolysaccharide (LPS) induced MDC, MIG and IP-10 ( p < 0.05, each comparison ) in THP-1 cells and human primary monocytes in a dose dependent manner "
IP-10 → LPS: " SB203580 [ p38-mitogen activated protein kinase ( MAPK ) inhibitor ] suppressed LPS induced MDC and IP-10 expression, and PD98059 ( ERK-MAPK inhibitor ) could only suppress LPS induced IP-10 , but not MDC expression "
MDC → LPS: " SB203580 [ p38-mitogen activated protein kinase ( MAPK ) inhibitor ] suppressed LPS induced MDC and IP-10 expression, and PD98059 ( ERK-MAPK inhibitor ) could only suppress LPS induced IP-10, but not MDC expression "
p-ERK → LPS: " LPS induced pp38 and p-ERK expression of THP-1 monocytic cells was suppressed by ketotifen "
MDC → LPS: " These data demonstrate that ketotifen is effective in down regulating LPS induced MDC , MIG and IP-10, which play important roles in the pathogenesis of airway inflammation "
IP-10 ⊣ p38: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "
IP-10 ⊣ ERK-MAPK: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "
IP-10 ⊣ ERK-MAPK: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "
MDC ⊣ p38: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "
MDC ⊣ ERK-MAPK: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "
MDC ⊣ ERK-MAPK: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "
p38 → LPS: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "
ERK-MAPK → LPS: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "
ERK-MAPK → LPS: " The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression "